23024-29-5

Basic information

• Product Name: DISUCCINIMIDYL SEBACATE
• Synonyms: SEBACIC ACID BIS(N-SUCCINIMIDYL) ESTER;DSSEB;DISUCCINIMIDYL SEBACATE;DI(N-SUCCINIMIDYL) SEBACATE;SEBACIC ACID BIS(N-SUCCINIMIDYL) ESTER 97+%;Di(N-succinimidyl) sebacate, DSSeb;2,5-Pyrrolidinedione, 1,1'-[(1,10-dioxo-1,10-decanediyl)bis(oxy)]bis-;Di(N-succinimidyl) Sebacate
• CAS NO: 23024-29-5
• Molecular Formula: C₁₈H₂₄N₂O₈
• Molecular Weight: 396.39
• Product Categories: pharmacetical;homoXlink
• Mol File: 23024-29-5.mol
• Article Data: 2

Chemical Properties

• Melting Point: 162-167 °C
• Boiling Point: 532.8°Cat760mmHg
• Flash Point: 276°C
• Appearance: /
• Density: 1.34g/cm³
• Storage Temp.: −20°C
• BRN: 6880740
• CAS DataBase Reference: DISUCCINIMIDYL SEBACATE(CAS DataBase Reference)
• NIST Chemistry Reference: DISUCCINIMIDYL SEBACATE(23024-29-5)
• EPA Substance Registry System: DISUCCINIMIDYL SEBACATE(23024-29-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 23024-29-5(Hazardous Substances Data)

Usage

Chemical Properties

14.1

Uses

amine reactive homobifunctional cross-linking reagent

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 111-20-6 1,10-decanedioic acid 

Relevant articles and documents

Preparation and properties of gelatin films incorporated with N-hydroxysuccinimide-activated end-bit binary acid

A series of novel cross-linkers, N-hydroxysuccinimide (NHS)-activated end-bit binary acid (NHS-C4, C5, C6, C8, C10, C14), were synthesised to modify gelatin films and the crosslinking effects were compared. Homogeneous films with the exception of the film crosslinked by NHS-C14 were observed and the thickness was measured using a scanning electron microscope. The section feature influenced by different film-treatment conditions was also recorded. The differential scanning calorimetry results indicated higher thermal stability. The water contact angles confirmed enhanced hydrophobicity. NHS-C6, which was used as a probe crosslinker, exhibited the best crosslinking effect that the content of the free -NH2 achieved was the lowest out of all the crosslinkers. The biodegradation results of gelatin films modified by NHS-C6 exhibited better degradation-resistance and excellent stability. In addition, the optimal experimental conditions were 45°C for 12 h when [NHS-C6]/[-NH2] = 2.5.