230287-26-0

Basic information

• Product Name: 1-benzyl-3-phenyl-4,5,6,7-tetrahydro-1H-indole
• Synonyms: 1-benzyl-3-phenyl-4,5,6,7-tetrahydro-1H-indole
• CAS NO: 230287-26-0
• Molecular Weight: 287.404
• Mol File: 230287-26-0.mol

Chemical Properties

• CAS DataBase Reference: 1-benzyl-3-phenyl-4,5,6,7-tetrahydro-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-3-phenyl-4,5,6,7-tetrahydro-1H-indole(230287-26-0)
• EPA Substance Registry System: 1-benzyl-3-phenyl-4,5,6,7-tetrahydro-1H-indole(230287-26-0)

Safety Data

• Hazardous Substances Data: 230287-26-0(Hazardous Substances Data)

Upstream product

• 5153-67-3 nitrostyrene 
• 108-94-1 cyclohexanone 
• 100-46-9 benzylamine 
• 4471-09-4 N-benzylcyclohexylimine 

Downstream Products

• 23073-17-8 3-phenyl-1-(phenylmethyl)-1H-indole 

Relevant articles and documents

Reaction of Cyclohexanones Imines with Substituted Nitroolefins. New Synthesis of Tetrahydroindole Derivatives

The Michael-type addition of cyclohexanones imines, reacting as their secondary enamine tautomers, to β-substituted nitroolefins is followed by a cyclization reaction with elimination of the nitro group to afford substituted tetrahydroindoles. When a 2-methylcyclohexanone imine is reacted, an unexpected inversion of the regioselectivity is observed when compared with β-substituted ethylenic esters, thus allowing to obtain also substituted tetrahydroindoles. - Keywords: Imines; Michael reactions; Regioselection; Indoles

Three-Component Ordered Annulation of Amines, Ketones, and Nitrovinylarenes: Access to Fused Pyrroles and Substituted Indoles under Metal-Free Conditions

An efficient synthesis of pyrroles and indoles has been developed via three-component ordered annulation of amines, ketones, and nitrovinylarenes. The reaction selectivity can be well controlled under metal-free conditions to afford the corresponding heterocyclic products in good yields.