23045-58-1Relevant academic research and scientific papers
An intramolecular Schmidt reaction of δ-azido N-acylbenzotriazoles
Liu, Chun-Fang,Cao, Zhi-Qi,Ding, Shao-Lei,Zhu, Jing,Gu, Peiming
, p. 1147 - 1151 (2021)
A Lewis acid promoted intramolecular Schmidt reaction of N-acylbenzotriazoles with alkyl azides was designed and realized. The benzotriazole was not only employed as an efficient activator for initiating the Schmidt rearrangement but also used as a powerful terminator for the subsequent nucleophilic trapping of the isocyanate ion and/or N-acyliminium ion from the rearrangement. Thirteen δ-azido N-acylbenzotriazoles were investigated, and the conversion afforded the desired benzotriazole-1carboxamides and lactams with good to excellent yields.
Friedel-Crafts Reactions. IV. The Use of Cyclic N-Formyl-2-Methoxyamines in Electrophilic Amidoalkylation of Aromatic Compounds
Malmberg, Mats,Nyberg, Klas
, p. 411 - 418 (2007/10/02)
Aromatic compounds react with cyclic N-formyl-2-methoxyamines in proton or Lewis acid catalyzed reactions, yielding 2-aryl substituted nitrogen heterocyclic compounds.These products are easily converted to the corresponding N-H and N-CH3 derivatives by acid hydrolysis and LiAlH4 reduction, respectively.
