2305-30-8

Basic information

• Product Name: 1,3-Cyclohexanedicarboxylic acid, (1R,3R)-rel-
• Synonyms: 1,3-Cyclohexanedicarboxylic acid, (1R,3R)-rel-;(1R,3R)-1,3 cyclohexanedicarboxylic acid;(1S*,3S*)-Cyclohexane-1,3-dicarboxylic acid;trans-1,3-CYCLOHEXANEDICARBOXYLIC ACID(WX191771)
• CAS NO: 2305-30-8
• Molecular Formula: C₈H₁₂O₄
• Molecular Weight: 172.17848
• Mol File: 2305-30-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 147-148 °C
• Boiling Point: 332.4±25.0 °C(Predicted)
• Appearance: /
• Density: 1.314±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.32±0.13(Predicted)
• CAS DataBase Reference: 1,3-Cyclohexanedicarboxylic acid, (1R,3R)-rel-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Cyclohexanedicarboxylic acid, (1R,3R)-rel-(2305-30-8)
• EPA Substance Registry System: 1,3-Cyclohexanedicarboxylic acid, (1R,3R)-rel-(2305-30-8)

Safety Data

• Hazardous Substances Data: 2305-30-8(Hazardous Substances Data)

Usage

General Description

1,3-Cyclohexanedicarboxylic acid, (1R,3R)-rel- is a chemical compound with the molecular formula C8H12O4. It is a cyclohexane derivative with two carboxylic acid functional groups, and its stereochemistry is defined by the (1R,3R)-rel- designation. 1,3-Cyclohexanedicarboxylic acid, (1R,3R)-rel- is commonly used as a starting material in the synthesis of various pharmaceuticals and organic molecules. It has a wide range of applications in the fields of organic chemistry, medicine, and material science. Additionally, it is used as a building block for the preparation of polymers and in the production of specialty chemicals.

Upstream product

• 121-91-5 isophthalic acid 
• 1610728-91-0 (S,S)-dibenzyl cyclohexyl 1,3-dicarboxylate 

Downstream Products

• 1610729-37-7 N-(5-((1S,3S)-3-(5-amino-1,3,4-thiadiazol-2-yl)cyclohexyl)-1,3,4-thiadiazol-2-yl)-2-(pyridin-2-yl)acetamide 
• 1610727-94-0 N-(5-((1S,3S)-3-(5-acetamido-1,3,4-thiadiazol-2-yl)cyclohexyl)-1,3,4-thiadiazol-2-yl)-2-(3-methoxyphenyl)acetamide 
• 1610728-92-1 5,5'-((1S,3S)-cyclohexane-1,3-diyl)bis(1,3,4-thiadiazol-2-amine) 
• 1610727-51-9 N,N'-(5,5'-((1S,3S)-cyclohexane-1,3-diyl)bis(1,3,4-thiadiazole-5,2-diyl))dibutyramide 
• 1610729-57-1 N-(5-((1S,3S)-3-(5-amino-1,3,4-thiadiazol-2-yl)cyclohexyl)-1,3,4-thiadiazol-2-yl)-2-(6-(3,3-difluoroazetidin-1-yl)pyridin-2-yl)acetamide 
• 1610729-38-8 N-(5-((1S,3S)-3-(5-amino-1,3,4-thiadiazol-2-yl)cyclohexyl)-1,3,4-thiadiazol-2-yl)acetamide 
• 1610728-72-7 N,N'-(5,5'-((1S,3S)-cyclohexane-1,3-diyl)bis(1,3,4-thiadiazole-5,2-diyl))bis(2-(2-methoxythiazol-4-yl)acetamide) 
• 1610728-66-9 N,N'-(5,5'-((1S,3S)-cyclohexane-1,3-diyl)bis(1,3,4-thiadiazole-5,2-diyl))bis(2-(1H-imidazol-4-yl)acetamide) 
• 1610728-52-3 N,N'-(5,5'-((1S,3S)-cyclohexane-1,3-diyl)bis(1,3,4-thiadiazole-5,2-diyl))bis(2-(3-(4-methylpiperazin-1-yl)phenyl)acetamide) 
• 1610728-45-4 N,N'-(5,5'-((1S,3S)-cyclohexane-1,3-diyl)bis(1,3,4-thiadiazole-5,2-diyl))bis(2-(5-(3,3-difluoroazetidin-1-yl)pyridin-2-yl)acetamide) 
• 1610728-46-5 N-(5-((1S,3S)-3-(5-acetamido-1,3,4-thiadiazol-2-yl)cyclohexyl)-1,3,4-thiadiazol-2-yl)-2-(5-(3,3-difluoroazetidin-1-yl)pyridin-2-yl)acetamide 
• 1610728-32-9 N,N'-(5,5'-((1S,3S)-cyclohexane-1,3-diyl)bis(1,3,4-thiadiazole-5,2-diyl))bis(2-(4-aminophenyl)acetamide) 
• 1610729-02-6 di-tert-butyl ((((5,5'-((1S,3S)-cyclohexane-1,3-diyl)bis(1,3,4-thiadiazole-5,2-diyl))bis(azanediyl))bis(2-oxoethane-2,1-diyl))bis(4,1-phenylene))dicarbamate 
• 1610727-88-2 N,N'-(5,5'-((1S,3S)-cyclohexane-1,3-diyl)bis(1,3,4-thiadiazole-5,2-diyl))bis(2-(6-methoxypyridin-2-yl)acetamide) 

Relevant articles and documents

COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES AS GLUTAMINASE INHIBITORS FOR TREATING CANCERS THEREOF

Provided are compounds of formula (I), wherein X, Y, Z, W, m, n, o, p, R1, R2 and R6 are defined as in the description. Pharmaceutical compositions and uses as glutaminase inhibitors for treating cancers thereof are also provided.

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