23074-10-4

Usage

Uses

Used in Chemical Synthesis:
5-Ethyl-2-furaldehyde is used as a key intermediate in the synthesis of various organic compounds and pharmaceuticals. Its unique structure and reactivity make it a valuable building block for the development of new molecules with potential applications in different fields.
Used in Pharmaceutical Industry:
5-Ethyl-2-furaldehyde is used as a starting material for the synthesis of N-(tert-butoxycarbonyl)-3-(benzoxazol-5-yl)alanine methyl ester derivatives. These derivatives have potential applications in the pharmaceutical industry, as they may exhibit biological activities and therapeutic properties. The synthesis of such derivatives can lead to the discovery of new drugs and treatments for various diseases and conditions.

InChI:InChI=1/C7H8O2/c1-2-6-3-4-7(5-8)9-6/h3-5H,2H2,1H3

Upstream product

• 3208-16-0 2-ethylfuran 
• 74-90-8 hydrogen cyanide 
• 68-12-2 N,N-dimethyl-formamide 
• 89114-36-3 5-ethylfurfuraldehyde oxime 
• 13529-27-6 2-(diethoxymethyl)furan 
• 75-03-6 ethyl iodide 
• 1450-58-4 anti-furfuraldoxime 

Downstream Products

• 123074-47-5 (4R,5S)-3-<(2'-R,3'R)-3'-(2''-(5''-ethylfuryl))-3'-hydroxy-2'-methylpropionyl>-4-methyl-5-phenyl-1,3-oxazolidin-2-one 
• 904681-97-6 methyl (2Z)-2-{[(benzyloxy)carbonyl]amino}-3-(5-ethyl-2-furyl)acrylate 
• 86505-42-2 3-ethylcyclopentanone 
• 51834-96-9 6-ethyl-3-hydroxypyridine 
• 159170-71-5 (3R,4S,5R,6R,8R,10R,11R,12S,13R,14S)-3,4-bis<(benzyloxy)methoxy>-5,13-dihydroxy-10,11-(isopropylidenedioxy)-4,6,8,10,12,14-hexamethylhexadec-15-en-7-one 
• 208659-28-3 (1R,5R,7S)-5-ethyl-2-(1,3-dithiolane)-7-(p-toluenesulfonyloxymethyl)-6,8-dioxabicyclo[3.2.1]octane 
• 208659-27-2 (1R,5R,7S)-5-ethyl-7-(p-toluenesulfonyloxymethyl)-6,8-dioxabicyclo[3.2.1]octan-2-one 
• 1027993-36-7 (R)-2-((S)-2-Benzyloxy-1-hydroxy-ethyl)-6-ethyl-6-hydroxy-6H-pyran-3-one 
• 208659-25-0 (1R,5R,7S)-7-benzyloxymethyl-5-ethyl-6,8-dioxabicyclo[3.2.1]oct-3-en-2-one 
• 208659-24-9 (1R,2S)-3-Benzyloxy-1-(5-ethyl-furan-2-yl)-propane-1,2-diol 
• 208659-23-8 2-((E)-3-Benzyloxy-propenyl)-5-ethyl-furan 

Relevant academic research and scientific papers

Synthesis of 2-substituted furanonaphthoquinones using directed metalation and cross coupling reactions

A synthetic method for the preparation of C-2 substituted furanonaphthoquinones from ortholithium-benzamide and the 2-furan- carboxaldehyde derivative is described. Four 2-alkyl-furanonaphthoquinones and the 2-phenyl-substituted were prepared via phathalide. This route has been shown to be general application to the synthesis of furanonaphthoquinones.

Preparation des acides alkyl et arylalkyl-5 methyl-2 benzofurannedicarboxyliques-6,7. Application a la synthese de derives de nouveaux heterocycles

Direct formation of 5-alkyl or arylalkyl 2-methylbenzofuran 6,7-dicarboxylic acid derivatives from Diels-Alder adducts of 5-alkyl or arylalkyl 2-acetonylfurans and dimethyl acetylenedicarboxylate is promoted by boron trifluoride etherate in methylene chloride at room temperature.The structures of these new compounds were established from their 1H and 13C nmr spectra.In 1,1,2,2-tetrachloroethane and in the presence of aluminium chloride, 5-arylalkylbenzofuran anhydrides undergo an intramolecular Friedel-Crafts acylations leading to new polycyclic benzofuran derivatives.

THE SYNTHESIS OF 2,5-DISUBSTITUTED FURANS

The dianion derived from the oxime of furfuraldehyde (1) reacts with electrophiles at the 5-position of the furan ring; subsequent hydrolysis of the oxime provides a useful method for the synthesis of 2,5-disubstituted furans.