23077-59-0 Usage
Uses
Used in Drug Development:
(E)-6-fluoro-3-(2-nitrovinyl)-1H-indole is used as a chemical intermediate for the development of new pharmaceuticals. Its unique structure and fluorescent properties make it a valuable compound for designing and synthesizing novel drugs with specific therapeutic targets.
Used in Fluorescence Microscopy:
In the field of biomedical research, (E)-6-fluoro-3-(2-nitrovinyl)-1H-indole is used as a fluorescent probe for fluorescence microscopy. Its ability to emit light upon excitation allows researchers to visualize and study biological processes and interactions at the molecular level, contributing to a better understanding of cellular mechanisms and potential drug targets.
Used in Biomedical Research:
(E)-6-fluoro-3-(2-nitrovinyl)-1H-indole is also used as a research tool in biomedical research. Its fluorescent properties enable the compound to be employed in various assays and experiments, aiding in the discovery of new biological insights and the development of innovative therapeutic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 23077-59-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,0,7 and 7 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 23077-59:
(7*2)+(6*3)+(5*0)+(4*7)+(3*7)+(2*5)+(1*9)=100
100 % 10 = 0
So 23077-59-0 is a valid CAS Registry Number.
23077-59-0Relevant academic research and scientific papers
Anti-cancer indole alkaloid compound, preparation method and application thereof
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Paragraph 0039; 0043-0045; 0081; 0085-0087, (2019/06/30)
The invention relates to an anti-cancer compound, which is an indole alkaloid series compound and has a general formula (I). Indole alkaloids have a very good inhibitory effect on multiple solid tumors, such as human breast cancer cells, and further have an inhibitory effect on tumor growth. The compound has an inhibitory effect on the growth of cancer cells, but has no inhibitory effect on the growth of normal cells. The compound can be used alone or in combination with other drugs.
Metal-Free Dearomatization: Direct Access to Spiroindol(en)ines in Batch and Continuous-Flow
Ranjan, Prabhat,Ojeda, Gerardo M.,Sharma, Upendra K.,Van der Eycken, Erik V.
supporting information, p. 2442 - 2446 (2019/01/29)
A metal-free, phosphine-catalyzed intramolecular “umpolung Michael addition” on alkynes to form spiroindol(en)ines is reported. This nucleophilic catalysis enables the formation of a wide scope of five- and six-membered spiroindol(en)ines in moderate to excellent yields in batch as well as under continuous-flow conditions. Triphenylphosphine-catalyzed nucleophilic activation of alkynes allows the exclusive formation of exo-product under mild reaction conditions.