23080-97-9Relevant academic research and scientific papers
Substituted pyrazino[1′,2′:1 ,5]pyrrolo[2,3-b]-indole-1,4-diones for cancer treatment
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Page/Page column 327, (2016/06/28)
The present application provides, among other things, a compound of Formula I-a and/or I-b, or a pharmaceutically acceptable salt thereof, wherein the variables are defined in the specification. The compounds of the invention are useful for treating various diseases including cancer.
Thiomethylation of ketones by sodium sulphide and formaldehyde
Ulendeyeva,Bayeva,Lyapina,Shmakov,Galkin
, p. 177 - 186 (2007/10/03)
The thiomethylation of propanol, butanol, cyclohexanone and acetophenone with a mixture of formaldehyde and sodium sulphide proceeds at 20°C and normal pressure for 1-7 hr. It has been established that the reactivity of ketones increases in the order butanone-cyclohexanone-propanone-acetophenone. The conversion of sodium sulphide depends on its initial concentration, the nature of the ketone, and the presence in the reaction medium of sodium hydroxide and ethyl alcohol. It has been shown that the reaction proceeds with the preferential formation of keto- and diketosulphides.
