23094-96-4

Basic information

• Product Name: 3-BROMO-4-METHOXY-BENZENESULFONYL CHLORIDE
• Synonyms: 3-bromo-4-methoxybenzenesulfonyl chloride(SALTDATA: FREE);3-broMo-4-Methoxybenzene-1-sulfonyl chloride;3-Bromo-4-methoxybenzenesulfonyl chloride 97%
• CAS NO: 23094-96-4
• Molecular Formula: C₇H₆BrClO₃S
• Molecular Weight: 285.55
• Mol File: 23094-96-4.mol
• Article Data: 7

Chemical Properties

• Melting Point: 83-88°C
• Boiling Point: 366°Cat760mmHg
• Flash Point: 175.1°C
• Appearance: /
• Density: 1.717g/cm³
• Vapor Pressure: 3.18E-05mmHg at 25°C
• Refractive Index: 1.569
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: 3-BROMO-4-METHOXY-BENZENESULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-4-METHOXY-BENZENESULFONYL CHLORIDE(23094-96-4)
• EPA Substance Registry System: 3-BROMO-4-METHOXY-BENZENESULFONYL CHLORIDE(23094-96-4)

Safety Data

• Hazard Codes: C
• Statements: 22-34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3261 8 / PGII
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 23094-96-4(Hazardous Substances Data)

Usage

General Description

3-Bromo-4-methoxy-benzenesulfonyl chloride is a chemical compound that comes under the category of organobromine compounds and organo-sulfonates. This chemical compound, with a molecular formula of C7H6BrClO3S, is notable for its bromine and chloride components. Generally used as an intermediate in organic synthesis, it is one of several benzene derivatives that carry a sulfonyl chloride group substituent. It also includes methoxy and bromine substituents. Detailed information about its physical and chemical properties, its stability, reactivity, or potential health effects isn't readily available, indicating that this compound's various aspects are possibly still under investigation or not widely studied.

InChI:InChI=1/C7H6BrClO3S/c1-12-7-3-2-5(4-6(7)8)13(9,10)11/h2-4H,1H3

Upstream product

• 578-57-4 2-bromoanisole 

Downstream Products

• 170288-10-5 3-Bromo-4-methoxy-N-phenyl-benzenesulfonamide 
• 358665-60-8 3-bromo-N-tert-butyl-4-methoxy-benzenesulfonamide 
• 20951-42-2 2-bromo-4-methanesulfonyl-1-methoxy-benzene 
• 1073265-07-2 N₁-(3-chloro-2-methylphenyl)-4-hydroxy-N₃-phenylbenzene-1,3-disulfonamide 
• 1073265-91-4 C₁₉H₂₃ClN₂O₅S 
• 1073265-92-5 C₁₄H₁₃Cl₂NO₅S₂ 
• 1041577-69-8 C₁₄H₁₅ClN₂O₃S 

Relevant articles and documents

THERAPEUTIC AGENT FOR INFLAMMATORY DISEASES, AUTOIMMUNE DISEASES, FIBROTIC DISEASES, AND CANCER DISEASES

A therapeutic agent for treating at least one disease selected from the group consisting of inflammatory diseases, autoimmune diseases, fibrotic diseases, and cancer diseases, comprising: at least one selected from the group consisting of a compound represented by the following general formula (1) and pharmacologically acceptable salts thereof as an active ingredient. [In the formula (1), R1 and R2 may be the same or different and each represents a hydrogen atom, a halogen atom, a hydroxyl group, a carboxy group, a cyano group, an optionally substituted C1-6 alkyl group et al.; R3 represents a hydrogen atom; R4 represents an optionally substituted 4- to 10-membered monocyclic heterocyclic group containing 1 to 4 heteroatoms selected from an oxygen atom, a nitrogen atom, and a sulfur atom; X represents a group represented by the following formula: -CH2-, - CH2-CH2-, -CH2-CH2-CH2-, or -CH2-O-CH2-; and Z represents a hydrogen atom or a hydroxyl group.]

N-(SUBSTITUTED-PHENYL)-SULFONAMIDE DERIVATIVES AS KINASE INHIBITORS

The invention relates to N-(substituted-phenyl)-sulfonamide compounds, which are extremely useful as inhibitors of protein kinases (e.g. PERK kinase) and accordingly can be used for the treatment of cell proliferative disorders, such as cancer, or diseases associated with activated unfolded protein response pathways, such as Alzheimer's disease. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds.

2-(2-HYDROXYBIPHENYL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE DERIVATIVES AS FACTOR VIIA INHIBITORS

The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders, cancer or rheumatoid arthritis. Processes for preparing these inhibitors are also disclosed.