2570-43-6

Usage

Uses

Used in Food Industry:
3,4-DIMETHOXYTHIOANISOLE is used as a flavoring agent for its unique sweet, creamy, and slightly floral scent, enhancing the taste profiles of various food products.
Used in Perfume and Cosmetic Industries:
In the realm of perfumery and cosmetics, 3,4-DIMETHOXYTHIOANISOLE serves as a fragrance ingredient, leveraging its distinctive aroma to create appealing scents in a range of products.
Used in Pharmaceutical Applications:
3,4-DIMETHOXYTHIOANISOLE is studied for its potential anti-inflammatory and antioxidant properties, suggesting its use as a component in pharmaceutical formulations to address specific health conditions.
Used in Skincare Applications:
Due to its potential anti-inflammatory and antioxidant characteristics, 3,4-DIMETHOXYTHIOANISOLE may be utilized in skincare products to provide beneficial effects on the skin, such as reducing inflammation and protecting against oxidative stress.
It is crucial to handle 3,4-DIMETHOXYTHIOANISOLE with care, as improper handling can result in skin, eye, and respiratory system irritation.

Upstream product

• 69845-06-3 3-hydroxy-4-methoxythiophenol 
• 77-78-1 dimethyl sulfate 
• 69845-05-2 4-Mercapto-2-methoxy-phenol 
• 90-05-1 2-methoxy-phenol 
• 624-92-0 Dimethyldisulphide 
• 2859-78-1 4-Bromoveratrole 
• 124-38-9 carbon dioxide 
• 700-96-9 3,4-dimethoxythiophenol 
• 23095-31-0 3,4-dimethoxybenzene-1-sulfonyl chloride 
• 91-16-7 1,2-dimethoxybenzene 
• 6096-21-5 2-methoxy-4-thiocyanatophenol 
• 531-37-3 2-methoxyphenyl benzoate 
• 74-88-4 methyl iodide 
• 69845-04-1 5-Thiocyano-2-methoxyphenylbenzoat 

Downstream Products

• 38417-24-2 1,2-dimethoxy-4-(methylsulfinyl)benzene 
• 38417-35-5 3,4-Dimethoxy-6-nitrophenylmethylsulfon 
• 2024-83-1 veratronitrile 
• 100-68-5 methyl-phenyl-thioether 
• 63624-32-8 1-(4,5-Dimethoxy-2-methylthiophenyl)-2-nitropropen 
• 79440-51-0 2-Methylthio-4,5-dimethoxyamphetamine 
• 63624-30-6 4,5-dimethoxy-2-(methylthio)benzaldehyde 

Relevant academic research and scientific papers

A Mononuclear Non-Heme Manganese(III)-Aqua Complex in Oxygen Atom Transfer Reactions via Electron Transfer

Metal-oxygen complexes, such as metal-oxo [M(O2-)], -hydroxo [M(OH-)], -peroxo [M(O22-)], -hydroperoxo [M(OOH-)], and -superoxo [M(O2?-)] species, are capable of conducting oxygen atom transfer (OAT) reactions with organic substrates, such as thioanisole (PhSMe) and triphenylphosphine (Ph3P). However, OAT of metal-aqua complexes, [M(OH2)]n+, has yet to be reported. We report herein OAT of a mononuclear non-heme Mn(III)-aqua complex, [(dpaq)MnIII(OH2)]2+ (1, dpaq = 2-[bis(pyridin-2-ylmethyl)]amino-N-quinolin-8-yl-acetamidate), to PhSMe and Ph3P derivatives for the first time; it is noted that no OAT occurs from the corresponding Mn(III)-hydroxo complex, [(dpaq)MnIII(OH)]+ (2), to the substrates. Mechanistic studies reveal that OAT reaction of 1 occurs via electron transfer from 4-methoxythioanisole to 1 to produce the 4-methoxythioanisole radical cation and [(dpaq)MnII(OH2)]+, followed by nucleophilic attack of H2O in [(dpaq)MnII(OH2)]+ to the 4-methoxythioanisole radical cation to produce an OH adduct radical, 2,4-(MeO)2C6H3S?(OH)Me, which disproportionates or undergoes electron transfer to 1 to yield methyl 4-methoxyphenyl sulfoxide. Formation of the thioanisole radical cation derivatives is detected by the stopped-flow transient absorption measurements in OAT from 1 to 2,4-dimethoxythioanisole and 3,4-dimethoxythioanisole, being compared with that in the photoinduced electron transfer oxidation of PhSMe derivatives, which are detected by laser-induced transient absorption measurements. Similarly, OAT from 1 to Ph3P occurs via electron transfer from Ph3P to 1, and the proton effect on the reaction rate has been discussed. The rate constants of electron transfer from electron donors, including PhSMe and Ph3P derivatives, to 1 are fitted well by the electron transfer driving force dependence of the rate constants predicted by the Marcus theory of outer-sphere electron transfer.

Nickel-Catalyzed Reversible Functional Group Metathesis between Aryl Nitriles and Aryl Thioethers

We describe a new functional group metathesis between aryl nitriles and aryl thioethers. The catalytic system nickel/dcype is essential to achieve this fully reversible transformation in good to excellent yields. Furthermore, the cyanide- and thiol-free reaction shows high functional group tolerance and great efficiency for the late-stage derivatization of commercial molecules. Finally, synthetic applications demonstrate its versatility and utility in multistep synthesis.

Reduction of CO2 with NaBH4/I2 for the Conversion of Thiophenols to Aryl Methyl Sulfides

We report a tandem reaction to realize reduction of carbon dioxide with thiophenols to generate aryl methyl sulfides under the NaBH4/I2 system with 18-crown-6 as the solvent. Thiophenols bearing electron-donating and electron-withdrawing groups are feasible in this reaction. Controlled experiment results indicate that 18-crown-6 plays a critical role in six-electron reduction of carbon dioxide.

Monomethylthio analogues of 1-(2,4,5-trimethoxyphenyl)-2-aminopropane

Regiospecific syntheses of the three monomethylthio analogues of 1-(2,4,5- trimethoxyphenyl)-2-aminopropane are described. The three isomeric amines were evaluated for potential psychotomimetic potency using the rabbit hyperthermia assay. Enantiomeric com