2311-13-9

Usage

Composition

One bromine atom and one fluorine atom

Physical State

Colorless, flammable gas

Odor

Faint, sweet

Common Uses

Refrigerant, production of pharmaceuticals, agrochemicals, and other organic compounds

Additional Applications

Solvent for cleaning and degreasing

Toxicity

Moderately toxic (risk to human health and environment if mishandled)

InChI:InChI=1/C2H4BrF/c1-2(3)4/h2H,1H3

Upstream product

• 353-36-6 1-fluoroethane 

Downstream Products

• 428517-57-1 2-(1-fluoroethylsulfanyl)benzothiazole 
• 267401-66-1 2-(2-fluoroethyl)-6-(4-fluorophenyl)-3-(2H)-pyridazinone 

Relevant academic research and scientific papers

Kinetics of the Photobromination of Fluoroethane. Estimate of the C-H Bond Dissociation Energies and the Heats of Formation of the CH3CHF and CH2CH2F Radicals

The gas-phase photobromination of fluoroethane was investigated in the temperature range 80-150°C in both the presence and absence of chloroethane as an external competitor. The rate constant for α-hydrogen abstraction in CH3CH2F was redetermined relative to that in CH3CH2Cl, and the abstraction of β-hydrogen was measured in the internal competition. The relative rates were combined with the known rate parameters for the bromination of C2H6 to obtain the absolute rate constants (cm3 mol-1 s-1): k(α) = (6.50±3.58) × 1012 exp [ - (10360±370)/RT] and k(β) = (3.42±1.95) × 1012 exp [ - (12950±390)/RT]. Using a justifiable approximation concerning the magnitude of the activation-energy difference for the reverse reactions between any two competitors with similar complexity the following thermochemical quantities (kcal mol-1) have been derived: ΔH° f(CH3CHF) = -16.8±2, ΔH° f(CH2CH2F) = -14.2±2, D° (CH3CHF-H) = 98.2±2, D° (CH2FCH2-H) = 100.8±2, and D° (CH2CH2-F) = 45.6±2. The influence of halogen substitution on the rate parameters of hydrogen abstraction from monohaloethanes is discussed.

FLP-Catalyzed Monoselective C-F Functionalization in Polyfluorocarbons at Geminal or Distal Sites

We report frustrated Lewis pair (FLP)-catalyzed monoselective C-F activation in a range of aliphatic polyfluorocarbons with equivalent geminal and distal C-F positions. This methodology can be applied to aromatic-, ether-, thioether-, and alkyl-supported fluoromethyl groups. We expand the range of FLP base partners that work with monoselective C-F activation to include sulfide. The activated products can be subsequently functionalized via SN2 substitutions, photoredox-alkylations, and Suzuki couplings.

A method for the preparation of ethylene fluorine bromine

The invention discloses a preparation method of 1-bromo-1-fluoroethylene.The preparation method comprises: two-stage bromination reaction and hydrogen bromide removal reaction; and has the characteristics of easily-available raw materials, low temperature of hot bromination reactions, high reaction yield, low cost, green, and environment-friendliness.