2311-90-2

Upstream product

• 99365-90-9 3-Acetamido-4-(4-methoxyphenyl)methyliden-1-phenyl-2-pyrazolin-5-on 
• 4149-06-8 3-amino-1-phenyl-2-pyrazolin-5-one 
• 75-36-5 acetyl chloride 
• 621-03-4 cyanoacetanilide 
• 61239-31-4 3-Oxo-3-anilinopropionamidoxime 
• 99365-98-7 4,4'-(p-Methoxyphenyl)methyliden-bis(3-acetamido-1-phenyl-2-pyrazolin-5-on) 
• 99378-04-8 N-{4-[1-(4-Dimethylamino-phenyl)-meth-(Z)-ylidene]-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-3-yl}-acetamide 
• 84104-44-9 5-Methyl-3-(2-oxo-2-anilinoethyl)-1,2,4-oxadiazole 

Downstream Products

• 99365-99-8 N-{4-[(3-Acetylamino-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)-p-tolyl-methyl]-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-3-yl}-acetamide 
• 99365-90-9 3-Acetamido-4-(4-methoxyphenyl)methyliden-1-phenyl-2-pyrazolin-5-on 
• 99378-04-8 N-{4-[1-(4-Dimethylamino-phenyl)-meth-(Z)-ylidene]-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-3-yl}-acetamide 
• 1116390-66-9 C₃₀H₂₀N₆O₆S₄ 
• 99365-98-7 4,4'-(p-Methoxyphenyl)methyliden-bis(3-acetamido-1-phenyl-2-pyrazolin-5-on) 
• 4149-06-8 3-amino-1-phenyl-2-pyrazolin-5-one 
• 99366-00-4 N-{4-[(3-Acetylamino-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)-phenyl-methyl]-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-3-yl}-acetamide 

Relevant academic research and scientific papers

Synthesis and purification of 3-N-acylaminopyrazolinones using a sequence of functionalized polymers

A parallel synthesis route to 3-acylaminopyrazolinones using a sequence of functionalized polymers has been developed. The polymers were utilized as both stoichiometric reagents and purification agents to allow for the clean formation of the desired target compounds.

Investigations on the Hydrolytic Stability of 4-Arylmethylidene-2-pyrazolin-5-ones

The 4-Arylmethylidene-2-pyrazoline-5-ones S are not stable under aqueous alkaline conditions.By the substitution of R3 with electron donor substituents S reacts preferably yielding aldehyde A and 2-pyrazoline-5-one P, while with electron acceptor substituents S forms 4,4'-arylmethylidene-bis-2-pyrazoline-5-one B.The intermediate of hydrolysis is 4-(arylhydroxymethyl)-2-pyrazoline-5-one SOH.The second order rate constants of the reactions of S with hydroxidions and with 2-pyrazoline-5-ones P(-) are determined.The dependence of the hydrolytic decomposition of S on the pH value, substituents and temperature is suitable for the intermediate formation of SOH.

Method for preparing 2-pyrazolin-5-ones from 1,2,4-oxadiazoles

A method for preparing 2-pyrazolin-5-ones from 1,2,4-oxadiazoles is described. The method comprises forming a liquid reaction system of a base catalyst and a 1,2,4-oxadiazole in an organic liquid reaction medium and heating the reaction system to a temperature sufficient to cause the 1,2,4-oxadiazole to be rearranged to a 2-pyrazolin-5-one.