23117-57-9

Usage

Uses

Used in Pharmaceutical Industry:
(6aR)-4,5,6,6a,7,8-Hexahydro-2,10,11,12-tetramethoxy-6-methylbenzo[6,7]cyclohept[1,2,3-ij]isoquinolin-1-ol is used as a potential pharmaceutical candidate due to its unique molecular structure and properties. Its optical inactivity and specific absorption maxima in the ultraviolet spectrum suggest that it may have potential applications in the development of new drugs or therapies.
Used in Chemical Research:
(6aR)-4,5,6,6a,7,8-Hexahydro-2,10,11,12-tetramethoxy-6-methylbenzo[6,7]cyclohept[1,2,3-ij]isoquinolin-1-ol can also be used in chemical research as a starting material or a reference compound for studying the properties and reactivity of similar complex organic molecules. Its characterization as the methiodide with a known melting point can be useful for comparative studies and understanding the behavior of related compounds.
Used in Material Science:
The unique molecular structure and optical properties of (6aR)-4,5,6,6a,7,8-Hexahydro-2,10,11,12-tetramethoxy-6-methylbenzo[6,7]cyclohept[1,2,3-ij]isoquinolin-1-ol may also find applications in material science, particularly in the development of new materials with specific optical or electronic properties. Its optical inactivity and absorption characteristics could be exploited in the design of advanced materials for various applications.

References

Badger, Bradbury., J. Chem. Soc., 445 (1960) Structure: Battersby et al., Chem. Commun., 450 (1967)

Upstream product

• 47764-93-2 1-(3',4',5'-trimethoxyphenethyl)-2-methyl-6-methoxy-7-benzyloxy-1,2,3,4-tetrahydroisoquinoline 
• 38726-41-9 7-hydroxy-6-methoxy-1-(3',4',5'-trimethoxyphenethyl)-N-methyl-1,2,3,4-tetrahydroisoquinoline 
• 186581-53-3 diazomethane 
• 1354-66-1 merenderine 
• 142542-98-1 merenderine N-oxide 

Relevant academic research and scientific papers

Use of Iron (III) Chloride in the Efficient Preparation of the Alkaloid Kreysigine by Oxidative Coupling

Reaction of the isoquinoline (1) with iron (III) chloride in dichloromethane followed by reductive treatment with methanol gives kreysigine (4) in 71percent yield; (2) gives (4) in lower yield as does treatment with water instead of methanol; (8) is the p

N-OXIDES OF HOMOAPORPHINE ALKALOIDS FROM MERENDERA RADDEANA

The alkaloid complex of the leaves, stems, seeds, and seed pods of Merendera raddeana Rgl. (family Liliaceae) has been investigated.A number of known tropolone alkaloids and their photochemical isomers have been isolated together with the homoaporphine bases merenderine, kreysigenine, and O-methylkreysigenine and their N-oxides, which have not been described in the literature.One of them (merenderine N-oxide) has been characterized by its physical constants and has been investigated by IR, PMR, and mass-spectral methods.By a study of the PMR spectrum of the fraction of neutral alkaloids from the leaves of the plant it has been established that it consists mainly of a mixture of equal amounts of colchicine and cornigerine.

Thallium in Organic Synthesis. 59. Alkaloid Synthesis via Intramolecular Nonphenolic Oxidative Coupling. Preparation of (+/-)-Ocoteine, (+/-)-Acetoxyocoxylonine, (+/-)-3-Methoxy-N-acetylnornantenine, (+/-)-Neolitsine, (+/-)-Kreysigine, (+/-)-O-Methylkreys

Reaction of 1,2-bis(3,4-dimethoxyphenyl)ethane, 1,3-bis(3,4-dimethoxyphenyl)propane, diveratryl ether, N-methyl-N-veratrylveratramide, and N-methylbis(3,4-dimethoxybenzyl)amine with thallium(III) trifluoroacetate (TTFA) and BF3.Et2O in CH2Cl2/TFA resulted