23130-26-9

Basic information

• Product Name: 2',4'-DIHYDROXY-3-(P-HYDROXYPHENYL)-PROPIOPHENONE
• Synonyms: 2',4,4'-TRIHYDROXYDIHYDROCHALCONE;2',4'-DIHYDROXY-3-(P-HYDROXYPHENYL)-PROPIOPHENONE;DAVIDIGENIN;2',4,4'-Trihydroxydihydrochalcone 2',4'-Dihydroxy-3-(p-hydroxyphenyl)-propiophenone;1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)-1-propanone
• CAS NO: 23130-26-9
• Molecular Formula: C₁₅H₁₄O₄
• Molecular Weight: 258.27
• Mol File: 23130-26-9.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 521.9°Cat760mmHg
• Flash Point: 283.5°C
• Appearance: /
• Density: 1.334g/cm³
• Vapor Pressure: 1.64E-11mmHg at 25°C
• Refractive Index: 1.655
• CAS DataBase Reference: 2',4'-DIHYDROXY-3-(P-HYDROXYPHENYL)-PROPIOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2',4'-DIHYDROXY-3-(P-HYDROXYPHENYL)-PROPIOPHENONE(23130-26-9)
• EPA Substance Registry System: 2',4'-DIHYDROXY-3-(P-HYDROXYPHENYL)-PROPIOPHENONE(23130-26-9)

Safety Data

• Hazardous Substances Data: 23130-26-9(Hazardous Substances Data)

Usage

General Description

2',4'-dihydroxy-3-(p-hydroxyphenyl)-propiophenone, also known as dihydroxyphenylpropionone or DHPP, is a chemical compound with the molecular formula C15H14O4. It is a derivative of propiophenone and contains two hydroxyl groups on the 2' and 4' positions of the molecule, as well as a p-hydroxyphenyl group. DHPP is used in the synthesis of pharmaceutical drugs and is also studied for its potential antioxidant properties. Additionally, it has been investigated for its ability to inhibit the enzyme monoamine oxidase, which plays a role in the metabolism of neurotransmitters in the brain. DHPP has also been researched for its potential applications in skincare and cosmetic products due to its antioxidant and anti-inflammatory properties.

InChI:InChI=1/C15H14O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-2,4-7,9,16-17,19H,3,8H2

Upstream product

• 20034-62-2 2'-Hydroxy-4'-(aethoxy-methoxy)-acetophenon 
• 128837-26-3 4-(ethyloxymethoxy)benzaldehyde 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 
• 123-08-0 4-hydroxy-benzaldehyde 
• 501-97-3 4-hydroxyphenylpropionic acid 
• 108-46-3 recorcinol 
• 961-29-5 isoliquirtigenin 
• 21562-22-1 4'-β-O-D-glucopyranosyl-4,2',4'-trihydroxydihydrochalcone 
• 13745-20-5 2',4,4'-trihydroxychalcone 

Downstream Products

• 1093945-46-0 schoepfin A 
• 21562-22-1 4'-β-O-D-glucopyranosyl-4,2',4'-trihydroxydihydrochalcone 
• 23140-78-5 4,4'-dihydroxy-dihydrochalcone-2'-O-β-D-glucopyranoside 
• 224644-18-2 7-hydroxy-3-[(4-hydroxyphenyl)methyl]-4H-chromen-4-one 

Relevant articles and documents

Antispasmodic and antioxidant activities of fractions and bioactive constituent davidigenin isolated from Mascarenhasia arborescens

Ethnopharmacological relevance: Mascarenhasia arborescens A. DC. (Apocynaceae) is used in traditional medicine in the North of Madagascar to treat intestinal disorders, intestinal spasms and diarrhoea. Aim of the study: The main objective of this work was

Glycosides of the leaves of Symplocos spp. (Symplocaceae)

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Chemoselective transfer hydrogenation of Α,Β-unsaturated carbonyls catalyzed by a reusable supported Pd nanoparticles on biomass-derived carbon

We herein report highly chemoselective transfer hydrogenation of α,β-unsaturated carbonyl compounds to saturated carbonyls with formic acid as a hydrogen donor over a stable and recyclable heterogeneous Pd nanoparticles (NPs) on N,O-dual doped hierarchical porous biomass-derived carbon. The synergistic effect between Pd NPs and incorporated heteroatoms on carbon plays a critical role on promoting the reaction efficiency. A series of α,β-aromatic and aliphatic unsaturated carbonyl compounds was selectively reduced to their corresponding saturated carbonyls in up to 97% isolated yields with good tolerance of various functional groups. In addition, the catalyst can be successively reused for at least 6 times without significant loss in reaction efficiency.

Anti-aging agent and for preventing aging of the skin (by machine translation)

PROBLEM TO BE SOLVED: To provide a fibroblast proliferation promoter, an MMP-1(matrix metalloprotease-1) activity inhibitor, an elastase activity inhibitor, a profilaggrin production-promoting activity, a filaggrin production promoter or an antiaging agent, based on having found a substance as an active ingredient for the agents, which has excellent fibroblast proliferation-promoting effect, MMP-1 activity inhibitory effect, elastase activity inhibitory effect, profilaggrin production-promoting effect, filaggrin production-promoting effect or antiaging effect.SOLUTION: The fibroblast proliferation promoter, the MMP-1(matrix metalloprotease-1) activity inhibitor, the elastase activity inhibitor, the profilaggrin production promoter, the filaggrin production promoter or the antiaging agent are each included with davidigenin as the active ingredient for the respective agents. Also, a skin care preparation for external use for antiaging is compounded with davidigenin.