23142-01-0 Usage
Chemical Properties
White to Off-White Solid
Originator
Asthma ,Nichiiko
Uses
Different sources of media describe the Uses of 23142-01-0 differently. You can refer to the following data:
1. Sigma receptor agonist
2. antibacterial, antiproliferative
3. An over-the-counter cough suppressant.
Manufacturing Process
1-Phenylcyclopentane carbonitrile was obtained by treatment of phenylacetonitrile with sodium amide and 1,4-dibrombutane.1-Phenyl-1-cyclopentane carboxylic acid was produced in the result of reaction of 1-phenylcyclopentane carbonitrile with sulfuric acid.1-Phenyl-1-cyclopentanecarbonyl chloride was obtained by treatment of 1phenyl-1-cyclopentane carboxylic acid with thionyl chloride.A mixture of 0.5 mol of 1-phenyl-1-cyclopentanecarbonyl chloride and of 0.5 mol of 2-(2-diethylaminoethoxy)ethanol (herein-after referred to as the amino alcohol) in 300 ml of toluene is heated under reflux for 20 h. The mixture is thereafter made alkaline by means of an aqueous solution of caustic soda and decanted; the toluenic layer is washed with water and concentrated in vacuo. The residue is distilled under high vacuum. After two fractional distillations, the 2-(2-diethylaminoethoxy)ethyl 1-phenylcyclopentane-carboxylate is obtained, in 85% yield. Boiling point 164°C/0.1 mm. Hg.
Brand name
Toclase (Pfizer).
Therapeutic Function
Antitussive
Biological Activity
A selective ligand for the σ 1 -site.
Check Digit Verification of cas no
The CAS Registry Mumber 23142-01-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,1,4 and 2 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 23142-01:
(7*2)+(6*3)+(5*1)+(4*4)+(3*2)+(2*0)+(1*1)=60
60 % 10 = 0
So 23142-01-0 is a valid CAS Registry Number.
InChI:InChI=1/C20H31NO3.2C6H8O7/c1-3-21(4-2)14-15-23-16-17-24-19(22)20(12-8-9-13-20)18-10-6-5-7-11-18;2*7-3(8)1-6(13,5(11)12)2-4(9)10/h5-7,10-11H,3-4,8-9,12-17H2,1-2H3;2*13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
