23142-01-0 Usage
Uses
Used in Pharmaceutical Industry:
CARBETAPENTANE CITRATE is used as an over-the-counter cough suppressant for treating coughs by reducing the cough reflex in the body. It is particularly effective in suppressing dry, non-productive coughs.
Used in Antimicrobial Applications:
In the field of antimicrobial research, CARBETAPENTANE CITRATE is used as an antibacterial agent, helping to combat bacterial infections by inhibiting their growth and proliferation.
Used in Anticancer Research:
CARBETAPENTANE CITRATE is also being explored for its potential use as an antiproliferative agent in cancer treatment. It may help to inhibit the growth and spread of cancer cells, making it a promising candidate for further research and development in oncology.
Originator
Asthma ,Nichiiko
Manufacturing Process
1-Phenylcyclopentane carbonitrile was obtained by treatment of phenylacetonitrile with sodium amide and 1,4-dibrombutane.1-Phenyl-1-cyclopentane carboxylic acid was produced in the result of reaction of 1-phenylcyclopentane carbonitrile with sulfuric acid.1-Phenyl-1-cyclopentanecarbonyl chloride was obtained by treatment of 1phenyl-1-cyclopentane carboxylic acid with thionyl chloride.A mixture of 0.5 mol of 1-phenyl-1-cyclopentanecarbonyl chloride and of 0.5 mol of 2-(2-diethylaminoethoxy)ethanol (herein-after referred to as the amino alcohol) in 300 ml of toluene is heated under reflux for 20 h. The mixture is thereafter made alkaline by means of an aqueous solution of caustic soda and decanted; the toluenic layer is washed with water and concentrated in vacuo. The residue is distilled under high vacuum. After two fractional distillations, the 2-(2-diethylaminoethoxy)ethyl 1-phenylcyclopentane-carboxylate is obtained, in 85% yield. Boiling point 164°C/0.1 mm. Hg.
Therapeutic Function
Antitussive
Biological Activity
A selective ligand for the σ 1 -site.
Check Digit Verification of cas no
The CAS Registry Mumber 23142-01-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,1,4 and 2 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 23142-01:
(7*2)+(6*3)+(5*1)+(4*4)+(3*2)+(2*0)+(1*1)=60
60 % 10 = 0
So 23142-01-0 is a valid CAS Registry Number.
InChI:InChI=1/C20H31NO3.2C6H8O7/c1-3-21(4-2)14-15-23-16-17-24-19(22)20(12-8-9-13-20)18-10-6-5-7-11-18;2*7-3(8)1-6(13,5(11)12)2-4(9)10/h5-7,10-11H,3-4,8-9,12-17H2,1-2H3;2*13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
