2315-81-3

Usage

Chemical Properties

off-white crytalline

InChI:InChI=1/C7H4ClNO/c8-6-3-5(4-9)1-2-7(6)10/h1-3,10H

Upstream product

• 142247-74-3 4-(benzyloxy)-3-chlorobenzonitrile 
• 1428636-98-9 C₈H₈ClNO₂ 
• 767-00-0 4-cyanophenol 
• 142247-73-2 4-acetoxy-3-chloro-benzonitrile 
• 102151-33-7 3-Chloro-4-methoxybenzonitrile 
• 66422-84-2 4-benzyloxy-3-chlorobenzaldehyde 
• 2420-16-8 4-hydroxy-3-chlorobenzaldehyde 
• 431998-28-6 C₁₄H₁₂NO₂Cl 
• 3964-56-5 4-bromo-2-chlorophenol 
• 544-92-3 copper(I) cyanide 

Downstream Products

• 101607-31-2 3,3'-dichloro-4,4'-but-2t-enediyldioxy-di-benzonitrile 
• 84437-19-4 3-Chloro-4-hydroxy-benzimidic acid methyl ester; hydrochloride 
• 943141-58-0 3-chloro-4-(trifluoromethanesulfonyloxy)benzonitrile 
• 943141-59-1 4-[3'-(1-adamantyl)-4'-benzyloxyphenyl]-3-chlorobenzonitrile 
• 943141-60-4 4-[3'-(1-adamantyl)-4'-hydroxyphenyl]-3-chlorobenzonitrile 
• 1079042-84-4 C₁₄H₆ClN₃O₃ 
• 1131891-03-6 3-chloro-4-(perfluorobutylsulfonyloxy)benzonitrile 
• 1135358-05-2 1,3-bis(2-chloro-4-cyanophenoxy)propane 
• 1047648-64-5 3-Chloro-4-[(1-methylprop-2-en-1-yl)oxy]benzonitrile 
• 744250-91-7 C₇H₅ClN₄O 
• 1690-07-9 2-Chlor-4-cyano-6-nitrophenyl-benzolsulfonat 
• 3849-65-8 2-Chlor-4-cyano-6-nitro-phenyl-oktanoat 
• 1690-06-8 2-Chlor-4-cyano-6-nitrophenyl-benzoat 
• 1690-04-6 3-Chlor-5-nitro-4-trichloracetoxy-benzonitril 

Relevant academic research and scientific papers

Visible-light photocatalytic activation of N-chlorosuccinimide by organic dyes for the chlorination of arenes and heteroarenes

A variety of arenes and heteroarenes are chlorinated in moderate to excellent yields using N-chlorosuccinimide (NCS) under visible-light activated conditions. A screening of known organic dye photocatalysts resulted in the identification of methylene green as the most efficient catalyst to use with NCS. According to mechanistic studies described within, the reaction is speculated to proceed via a single electron oxidation of NCS utilizing methylene green under visible-light photoredox pathway. The photo-oxidation of NCS amplifies the electrophilicity of the chlorine atom of the NCS, thus leading to enhanced reactivity as a chlorinating reagent with aromatic substrates.

TRICYCLIC IMIDAZOLE COMPOUNDS AS INHIBITORS OF TRYPTOPHAN HYDROXYLASE

The present invention relates to compounds of the formula (I), wherein R1a, R1b, R2, R3, and X are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to thei

TRICYCLIC PIPERIDINE COMPOUNDS

The present invention relates to compounds of the formula (I), wherein R, R1a, R1b, R2, R3, and X are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), to methods for the preparation of such compounds of formula (I), and especially to their use as TPH modulators.

Ruthenium-catalyzed intramolecular selective halogenation of O-methylbenzohydroximoyl halides: A new route to halogenated aromatic nitriles

The intramolecular halogenation of O-methylbenzohydroximoyl halides in the presence of a Ru catalyst and the ligand diphenylacetylene afforded halo substituted aromatic nitriles in a highly regioselective manner. Further, substituted nitriles were converted into substituted tetrazole derivatives in the presence of NaN3 and I2.

An adamantyl-substituted retinoid-derived molecule that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nuclear receptor: Effects of modifying its carboxylate group on apoptosis, proliferation, and

Apoptotic and antiproliferative activities of small heterodimer partner (SHP) nuclear receptor ligand (E)-4-[3′-(1-adamantyl)-4′- hydroxyphenyl]-3-chlorocinnamic acid (3-Cl-AHPC), which was derived from 6-[3′-(1-adamantyl)-4′-hydroxyphenyl]-2-naphthalenec

Substituted triazole derivatives as oxytocin antagonists

The present invention relates to substituted triazoles of formula (I), uses thereof, processes for the preparation thereof and compositions containing said compounds. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction.

Process for preparing aromatic nitriles

The invention relates to obtaining aromatic nitriles of general formula: (R)n --C6 H4 --CN, where n=1, 2 or 3, and the rest R, identical or different represent an atom of hydrogen, chlorine or bromine or an alkyl, aryl, alkoxy, alkylamino, hydroxy or amino group, by a process comprising decarboxylating ammoxidation reaction, in an alkaline aqueous medium, at a pH higher than, or equal to, 13, in the presence of a catalyst based on one or several transition metals and an alkaline hydroxide, applied to an arylglyoxylic acid free or salified, of the formula: (R)n --C6 H4 --CO--COOH (where n and R have the above-mentioned meanings), or to one of its functional derivatives of the lactone, lactame or C1 -C3 -alkyl ester type.