23155-00-2 Usage
Uses
Used in Pharmaceutical Industry:
rac trans-4-Hydroxy Glyburide is used as an antidiabetic agent for its ability to effectively manage blood sugar levels in patients with diabetes. Its role in regulating glucose metabolism makes it a valuable asset in the treatment and management of this chronic condition.
Used in Research and Development:
In addition to its practical applications, rac trans-4-Hydroxy Glyburide is also utilized in research and development within the pharmaceutical and biotechnology industries. Its chemical properties and metabolic role provide valuable insights into the development of new drugs and therapies for diabetes and related metabolic disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 23155-00-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,1,5 and 5 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 23155-00:
(7*2)+(6*3)+(5*1)+(4*5)+(3*5)+(2*0)+(1*0)=72
72 % 10 = 2
So 23155-00-2 is a valid CAS Registry Number.
23155-00-2Relevant academic research and scientific papers
Hydroxyl-Substituted sulfonylureas as potent inhibitors of specific [3H]Glyburide binding to rat brain synaptosomes
Hill, Ronald A.,Rudra, Sonali,Peng, Bo,Roane, David S.,Bounds, Jeffrey K.,Zhang, Yang,Adloo, Ahmad,Lu, Tiansheng
, p. 2099 - 2113 (2007/10/03)
We are seeking to discover potent CNS-active sulfonylureas with structural features that allow for the formation of several types of prodrugs. We report herein the syntheses of compounds comprising an initial series of hydroxyl-substituted analogues of the potent ATP-sensitive potassium channel blockers glyburide (glibenclamide) and gliquidone. Somewhat unexpectedly, several of the compounds were found to be comparably potent to glyburide as inhibitors of specific [3H]glyburide binding in rat brain preparations.
