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1-(4-hydroxyphenyl)-3-propan-2-ylurea, also known as hydroxy acetophenone, is a chemical compound with the molecular formula C11H13NO2. It is a phenylurea derivative characterized by its white crystalline solid appearance and solubility in organic solvents. 1-(4-hydroxyphenyl)-3-propan-2-ylurea is recognized for its versatile applications in various industries, primarily due to its antimicrobial, antifungal, and anti-inflammatory properties.

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  • 23159-73-1 Structure
  • Basic information

    1. Product Name: 1-(4-hydroxyphenyl)-3-propan-2-ylurea
    2. Synonyms: 1-(4-hydroxyphenyl)-3-propan-2-ylurea;1-(4-HYDROXYPHENYL)-3-ISOPROPYL UREA
    3. CAS NO:23159-73-1
    4. Molecular Formula: C10H14N2O2
    5. Molecular Weight: 194.233
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 23159-73-1.mol
  • Chemical Properties

    1. Melting Point: 166-168 °C
    2. Boiling Point: 320.4°C at 760 mmHg
    3. Flash Point: 147.6°C
    4. Appearance: /
    5. Density: 1.19g/cm3
    6. Vapor Pressure: 0.00017mmHg at 25°C
    7. Refractive Index: 1.592
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. PKA: 10.28±0.26(Predicted)
    11. CAS DataBase Reference: 1-(4-hydroxyphenyl)-3-propan-2-ylurea(CAS DataBase Reference)
    12. NIST Chemistry Reference: 1-(4-hydroxyphenyl)-3-propan-2-ylurea(23159-73-1)
    13. EPA Substance Registry System: 1-(4-hydroxyphenyl)-3-propan-2-ylurea(23159-73-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 23159-73-1(Hazardous Substances Data)

23159-73-1 Usage

Uses

Used in Pharmaceutical Industry:
1-(4-hydroxyphenyl)-3-propan-2-ylurea is used as an intermediate in the synthesis of pharmaceuticals for its antimicrobial, antifungal, and anti-inflammatory properties. It contributes to the development of drugs that address a range of health conditions by targeting microbial and fungal infections, as well as reducing inflammation.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(4-hydroxyphenyl)-3-propan-2-ylurea is utilized as an intermediate in the production of agrochemicals. Its antimicrobial and antifungal characteristics make it valuable for creating products that protect crops from diseases and pests, thereby enhancing agricultural productivity.
Used in Cosmetic and Personal Care Industry:
1-(4-hydroxyphenyl)-3-propan-2-ylurea is also employed in the cosmetic and personal care industries. Its anti-inflammatory and antimicrobial properties are beneficial for formulating products that promote skin health and hygiene, offering protection against harmful microorganisms and supporting skin recovery processes.

Check Digit Verification of cas no

The CAS Registry Mumber 23159-73-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,1,5 and 9 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 23159-73:
(7*2)+(6*3)+(5*1)+(4*5)+(3*9)+(2*7)+(1*3)=101
101 % 10 = 1
So 23159-73-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N2O2/c1-7(2)11-10(14)12-8-3-5-9(13)6-4-8/h3-7,13H,1-2H3,(H2,11,12,14)

23159-73-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(4-hydroxyphenyl)-3-propan-2-ylurea

1.2 Other means of identification

Product number -
Other names 1-(4-hydroxyphenyl)-3-propan-2-yl-urea

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:23159-73-1 SDS

23159-73-1Relevant articles and documents

Synthesis and SAR studies of potent H+/K+-ATPase and anti-inflammatory activities of symmetrical and unsymmetrical urea analogues

Rakesh, Kadalipura P.,Darshini, Nanjudappa,Vidhya, Sunnadadoddi L.,Rajesha,Mallesha, Ningegowda

, p. 1675 - 1681 (2017/06/27)

A sequence of symmetrical and unsymmetrical urea derivatives 1–24 were synthesized and characterized by standard spectroscopic techniques. The synthesized analogues were tested for their in vitro H+/K+-ATPase and anti-inflammatory activities. The majority of the compounds showed outstanding activity, compared to that of omeprazole and indomethacin, usual standard drugs of antiulcer and anti-inflammatory, respectively. In particular, hydroxy, methyl, and methoxy derivatives 13–24 were the most active compounds possessing a significant amplify for diverse substituents on the benzene ring thus, contributing positively to gastric ulcer inhibition. Compounds 1–3 and 22–24 showed excellent anti-inflammatory activity due to the presence of electron-withdrawing groups (Cl and F) on the molecule.

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