23173-76-4

Basic information

• Product Name: 1-BENZYL-4-(ETHOXYCARBONYLMETHYL)PIPERAZINE
• Synonyms: 1-BENZYL-4-(ETHOXYCARBONYLMETHYL)PIPERAZINE;N-Benzyl-N-(carboethoxymethyl)piperazine
• CAS NO: 23173-76-4
• Molecular Formula: C₁₅H₂₂N₂O₂
• Molecular Weight: 262.35
• EINECS: -0
• Mol File: 23173-76-4.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 155-160°C 0,8mm
• Flash Point: 155-160°C/0.8mm
• Appearance: /
• Density: 1.088g/cm³
• Vapor Pressure: 2.17E-05mmHg at 25°C
• Refractive Index: 1.5183
• PKA: 6.63±0.10(Predicted)
• BRN: 196868
• CAS DataBase Reference: 1-BENZYL-4-(ETHOXYCARBONYLMETHYL)PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BENZYL-4-(ETHOXYCARBONYLMETHYL)PIPERAZINE(23173-76-4)
• EPA Substance Registry System: 1-BENZYL-4-(ETHOXYCARBONYLMETHYL)PIPERAZINE(23173-76-4)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 23173-76-4(Hazardous Substances Data)

Usage

General Description

1-Benzyl-4-(ethoxycarbonylmethyl)piperazine, also known as ECP, is a chemical compound that belongs to the class of piperazine derivatives. It is a psychoactive substance that has gained popularity as a recreational drug due to its stimulant and empathogenic effects. ECP is often sold in the form of tablets or powder and is commonly used in party and club settings. The compound acts as a serotonin-norepinephrine-dopamine releasing agent, resulting in increased levels of these neurotransmitters in the brain. ECP is known to induce feelings of euphoria, increased energy, and heightened sensory perception. However, it also poses a risk of negative side effects such as increased heart rate, anxiety, and potential neurotoxicity with prolonged or excessive use. Due to these risks, the compound is regulated in many countries and is illegal to possess or distribute without proper authorization.

InChI:InChI=1/C15H22N2O2/c1-2-19-15(18)13-17-10-8-16(9-11-17)12-14-6-4-3-5-7-14/h3-7H,2,8-13H2,1H3

Upstream product

• 5321-63-1 dihydrochloride salt of 1-benzylpiperazine 
• 105-39-5 chloroacetic acid ethyl ester 
• 2759-28-6 1-phenylmethylpiperazine 
• 105-36-2 ethyl bromoacetate 
• 623-73-4 diazoacetic acid ethyl ester 
• 100-44-7 benzyl chloride 
• 40004-08-8 1-(Ethoxycarbonylmethyl)piperazine 

Downstream Products

• 24632-70-0 2-(4-benzylpiperazin-1-yl)acetohydrazide 
• 1449679-59-7 (E)-2-(4-benzylpiperazin-1-yl)-N'-((3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)acetohydrazide 
• 1449679-58-6 2-(4-benzylpiperazin-1-yl)-N'-(2-(bis(pyridin-2-ylmethyl)amino)acetyl)acetohydrazide 
• 1075725-60-8 2-(4-benzylpiperazin-1-yl)-N'-(3,5-diallyl-2-hydroxybenzylidene)acetohydrazide 
• 315183-21-2 2-(4-benzylpiperazin-1-yl)-N-[(2-hydroxy-3-prop-2-enylphenyl)methylideneamino]acetamide 
• 1075725-59-5 C₂₀H₂₃N₇O₂ 
• 1075725-57-3 N'-(3-allyl-2-methoxybenzylidene)-2-(4-benzylpiperazin-1-yl)acetohydrazide 
• 1075725-71-1 2-(4-benzylpiperazin-1-yl)-N-(2-hydroxyphenethyl)acetamide 
• 315183-08-5 de-allyl PAC-1 
• 1075725-70-0 2-(4-benzylpiperazin-1-yl)-N-(2-hydroxybenzyl)acetamide 
• 121677-69-8 1-benzyl-4-(2-hydroxy-2,2-diphenyl-ethyl)-1-methyl-piperazinium; methyl sulfate 
• 121968-99-8 1-benzyl-4-(2-hydroxy-2,2-diphenyl-ethyl)-1-methyl-piperazinium; bromide 
• 102946-58-7 2-(4-phenethyl-piperazino)-1,1-diphenyl-ethanol 
• 109614-68-8 1,1-diphenyl-2-(piperazin-1-yl)ethan-1-ol 

Relevant articles and documents

Synthesis and initial in vitro biological evaluation of two new zinc-chelating compounds: Comparison with TPEN and PAC-1

The lipophilic, cell-penetrating zinc chelator N,N,N′,N′,- tetrakis(2-pyridylmethyl) ethylenediamine (TPEN, 1) and the zinc chelating procaspase-activating compound PAC-1 (2) both have been reported to induce apoptosis in various cell types. The relations

DESIGN, SYNTHESIS AND EVALUATION OF PROCASPASE ACTIVATING COMPOUNDS AS PERSONALIZED ANTI-CANCER DRUGS

Compositions and methods are disclosed in embodiments relating to induction of cell death such as in cancer cells. Compounds and related methods for synthesis and use thereof, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells are disclosed. Compounds are disclosed that have lower neurotoxicity effects than other compounds.

Ruthenium(III) chloride-catalyzed efficient protocol for ethyl diazoacetate insertion into the N-H bond of secondary amines

Ruthenium(III) chloride (1 mol%) alone can catalyze the insertion of ethyl diazoacetate into N-H bonds of various structurally and electronically diverse secondary cyclic amines under solvent-free conditions to afford the corresponding glycine esters in g