23191-75-5

Upstream product

• 54889-50-8 diethyl 3-amino-2-pentene-1,5-dioate 
• 39561-91-6 ethyl 3-oxo-2-<<2-(trifluoromethyl)phenyl>methylene>butanoate 
• 447-61-0 2-Trifluoromethylbenzaldehyde 
• 141-97-9 ethyl acetoacetate 
• 64-17-5 ethanol 

Downstream Products

• 126179-82-6 diethyl 2-<(diethoxyphosphonyl)methyl>-1,4-dihydro-6-methyl-4-<2-(trifluoromethyl)phenyl>-3,5-pyridinedicarboxylate 
• 126179-81-5 diethyl 1,4-dihydro-2-methyl-4-<2-(trifluoromethyl)phenyl>-6-<(trimethylsilyl)methyl>-3,5-pyridinedicarboxylate 
• 126179-84-8 3,5-bis(ethoxycarbonyl)-1,4-dihydro-6-methyl-4-<2-(trifluoromethyl)phenyl>-2-pyridineacetic acid sodium salt 
• 110646-22-5 diethyl 2-<<(2-aminoethyl)thio>methyl>-1,4-dihydro-6-methyl-4-<2-(trifluoromethyl)phenyl>-3,5-pyridinedicarboxylate 
• 126199-98-2 diethyl 1,4-dihydro-6-methyl-2-<(methylsulfonyl)methyl>-4-<2-(trifluoromethyl)phenyl>-3,5-pyridinedicarboxylate 
• 126179-80-4 ethyl 1,4,7,8-tetrahydro-2,7,7-trimethyl-5-oxo-4-<2-(trifluoromethyl)phenyl>-5H-pyrano<4,3-b>pyridine-3-carboxylate 
• 126179-79-1 diethyl 1,4-dihydro-2-(2-hydroxy-2-methylpropyl)-6-methyl-4-<2-(trifluoromethyl)phenyl>-3,5-pyridinedicarboxylate 
• 115015-34-4 (2Z,3α,4β)-(+/-)-diethyl 2-(2-ethoxy-2-oxoethylidene)-1,2,3,4-tetrahydro-6-methyl-4-<2-(trifluoromethyl)phenyl>-3,5-pyridinedicarboxylate 
• 126179-83-7 diethyl 2-<<(butylamino)carbonyl>methyl>-1,4-dihydro-6-methyl-4-<2-(trifluoromethyl)phenyl>-3,5-pyridinedicarboxylate 
• 85615-21-0 ethyl 2-methyl-4-(2-trifluoromethylphenyl)-5-oxo-1,4-dihydro-5,7-dihydrofuro[3,4-b]pyridine-3-carboxylate 
• 126335-10-2 2-methyl-3-ethoxycarbonyl-4-(2'-trifluoromethylphenyl)-5-oxo-5,7-dihydrofuro<3,4-b>pyridine 
• 53219-38-8 2,6-dimethyl-4-(2-trifluoromethyl-phenyl)-4H-pyridine-1,3,5-tricarboxylic acid triethyl ester 
• 145344-17-8 ethyl 5-hydroxy-2-methyl-4-(2-(trifluoromethyl)phenyl)-1,6-naphthyridine-3-carboxylate 
• 111196-43-1 (3S,4R)-2-[1-Ethoxycarbonyl-meth-(Z)-ylidene]-6-methyl-4-(2-trifluoromethyl-phenyl)-1,2,3,4-tetrahydro-pyridine-3,5-dicarboxylic acid diethyl ester 

Relevant academic research and scientific papers

1,4-DIHYDRONAPHTHYRIDINE DERIVATIVES

A compound of formulae (I) or a prodrug of the compound or a pharmaceutically acceptable salt thereof of the compound or prodrug, wherein the substituents are as defined in the specification, pharmaceutical compositions containing the compounds useful as

2-(2-Aryl-2-oxoethylidene)-1,2,3,4-tetrahydropyridines. Novel isomers of 1,4-dihydropyridine calcium channel blockers

The title compounds are novel double bond isomers of 1,4-dihydropyridine-type calcium channel blockers (CCB). These derivatives were prepared by using the Hantzsch dihydropyridine synthesis. The assignment of structure was based on spectroscopic data and