23195-60-0

Usage

Structure

Five-membered aromatic ring with three nitrogen atoms, with a 4-methylphenyl group attached to the 3-position

Type

Derivative of 1,2,4-triazole

Potential applications

Pharmaceuticals, agrochemicals, and materials science

Usage

Building block in the synthesis of biologically active compounds and functional materials

Biological and physical properties

Diverse

Upstream product

• 54682-94-9 N-(1,2,2,2-tetrachloroethyl)-4-methylbenzimidoyl chloride 
• 619-55-6 para-methylbenzamide 
• 83326-45-8 6-Imino-1-phenyl-2-p-tolyl-1,6-dihydro-pyrimidine-5-carbonitrile 
• 64781-78-8 3-diazo-3H-[1,2,4]triazole 
• 108-88-3 toluene 

Downstream Products

• 1181214-34-5 4-(1-(4-(perfluoroethoxy)phenyl)-1H-1,2,4-triazol-3-yl)benzaldehyde 
• 1181214-35-6 1-(4-pentafluoroethyloxy-phenyl)-3-p-tolyl-1H-[1,2,4]triazole 
• 1265175-56-1 1-(4-Pentafluoroethyl-phenyl)-3-p-tolyl-1H-[1,2,4]triazole 
• 1181214-36-7 4-(1-(4-(pentafluoroethoxy)phenyl)-1H-1,2,4-triazol-3-yl)benzoic acid 
• 1181214-37-8 4-{1-[4-(pentafluoroethoxy)phenyl]-1H-1,2,4-triazol-3-yl}benzoyl azide 
• 1181214-40-3 4-[1-(4-pentafluoroethyl-phenyl)-1H-[1,2,4]triazol-3-yl]-benzaldehyde 
• 1265175-61-8 3-(4-nitrooxymethyl-phenyl)-1-(4-pentafluoroethyl-phenyl)-1H-[1,2,4]triazole 
• 1417885-95-0 4-(1-(4-(perfluoropropyl)phenyl)-1H-1,2,4-triazol-3-yl)benzoyl azide 
• 1417885-94-9 4-(1-(4-(perfluoropropyl)phenyl)-1H-1,2,4-triazol-3-yl)benzoic acid 
• 1417885-92-7 1-(4-(perfluoropropyl)phenyl)-3-(p-tolyl)-1H-1,2,4-triazole 

Relevant academic research and scientific papers

A new, high-yield synthesis of 3-aryl-1,2,4-triazoles

A convenient new synthetic approach to 3-aryl-1,2,4-triazoles has been developed. Chloralamides were obtained by high yield reactions between benzamides and chloral hydrate. These reacted with a phosphorus pentachloride/phosphorus oxychloride mixture unde

SUBSTITUENT AND COORDINATION EFFECTS IN SINGLET REACTIONS OF 3-DIAZO-3H-1,2,4-TRIAZOLES WITH SUBSTITUTED BENZENES AND NITRO COMPOUNDS

3-Diazo-3H-1,2,4-triazoles convert to singlet 3H-1,2,4-triazol-3-ylidenes which (1) effect directed electrophilic substitutions of benzenes and (2) coordinate with benzenoid substituents and nitro compounds to give decomposition or rearrangement products.

SYNTHESIS OF TRIAZOLES AND OXADIAZOLES FROM 2-ARYL-3-PHENYL-4-IMINO-5-CYANO-3,4-DIHYDROPYRIMIDINES

2-Aryl-3-phenyl-4-imino-5-cyano-3,4-dihydropyrimidines I were transformed to 1,2,4-triazoles II,IV and 1,2,4-oxadiazoles III by treatment with hydrazine, arylhydrazines or hydroxylamine in yields up to 90percent.