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P-methyl-α-bromoisobutyranilide is a chemical compound with the molecular formula C11H12BrNO. It is an organic compound that belongs to the class of amides, specifically a substituted benzamide. The structure of p-methyl-α-bromoisobutyranilide consists of a benzene ring with an amide group attached to the para position (the fourth carbon), and an α-bromoisobutyryl group attached to the nitrogen atom of the amide. The α-bromoisobutyryl group is a substituted acyl group, which contains a bromine atom and an isobutyl group. p-methyl-α-bromoisobutyranilide is known for its potential applications in the synthesis of various pharmaceuticals and agrochemicals, as well as its use as an intermediate in organic chemistry. Due to its reactivity and functional groups, p-methyl-α-bromoisobutyranilide can participate in various chemical reactions, such as nucleophilic substitutions, making it a valuable building block in the creation of more complex molecules.

2322-49-8

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2322-49-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2322-49-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,3,2 and 2 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 2322-49:
(6*2)+(5*3)+(4*2)+(3*2)+(2*4)+(1*9)=58
58 % 10 = 8
So 2322-49-8 is a valid CAS Registry Number.

2322-49-8Relevant academic research and scientific papers

Bromo-nitro substitution on a tertiary α carbon - A previously uncharacterized facet of the Kornblum substitution

Leonard, Matthew J.,McKay, Peter G.,Lingham, Anthony R.

, p. 76401 - 76418 (2015/09/22)

Sodium nitrite in dimethylformamide substitutes nitro for bromine alpha to an amide carbonyl in high yield at a tertiary site. Hammett plots show a strongly positive ρ value (+0.67), indicating a negatively-charged transition state, in contrast to the typical SN1/SN2 mechanism domain for Kornblum substitutions. 2015

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