232264-73-2Relevant academic research and scientific papers
Aryl(TMP)iodonium Tosylate Reagents as a Strategic Entry Point to Diverse Aryl Intermediates: Selective Access to Arynes
Nilova, Aleksandra,Metze, Bryan,Stuart, David R.
, p. 4813 - 4817 (2021/06/28)
Arenes are broadly found motifs in societally important molecules. Access to diverse arene chemical space is critically important, and the ability to do so from common reagents is highly desirable. Aryl(TMP)iodonium tosylates provide one such access point
On the use of 2-(trimethylsilyl)iodobenzene as a benzyne precursor
Crossley, James A.,Kirkham, James D.,Browne, Duncan L.,Harrity, Joseph P. A.
experimental part, p. 6608 - 6610 (2011/01/12)
A mild method for the generation of benzynes from 2-(trimethylsilyl) iodobenzene derivatives is reported. The employment of silver fluoride in conjunction with caesium fluoride is key for promoting useful levels of elimination and providing benzyne derived products in good yields. Moreover, the substrates are accessed by a novel alkynyl iodide cycloaddition.
