23228-15-1Relevant articles and documents
Design, Synthesis, and Testing of Potential Antisickling Agents. 7. Ethacrynic Acid Analogues
Abraham, D. J.,Mehanna, A. S.,Williams, F. S.,Cragoe, E. J.,Woltersdorf, O. W.
, p. 2460 - 2467 (2007/10/02)
In search of a drug to treat sickle cell anemia, several analogues of the diuretic ethacrynic acid (ECA) have been synthesized and found equivalent in antigelling potency to ECA, but they have moderate or little diuretic activity.Structure-activity studie