23235-05-4Relevant articles and documents
Synthesis of 3-amlno-8-azachromans and 3-amino-7-azabenzofurans via inverse electron demand dlels-alder reaction
Badarau, Eduard,Suzenet, Franck,Finaru, Adriana-Lusninita,Guillaumet, Gerald
experimental part, p. 3619 - 3627 (2009/12/01)
The synthesis of 3-amino-8-azachromans and 3-amino-7-azabenzofurans derivatives is reported. The synthetic strategy is based on an inverse electron demand Diels-Alder approach, which employs 1,2,4-triazines that are judiciously substituted with amino alkynols. This approach permits the variation of the substituent on the aromatic core and on the amine moiety, as well as of the size of the nonaromatic ring.
Synthesis of highly functionalized phenylalanine derivatives via cross-enyne metathesis reactions
Kotha, Sambasivarao,Halder, Somnath,Brahmachary, Enugurthi
, p. 9203 - 9208 (2007/10/03)
A new method for the synthesis of constrained phenylalanine derivatives is described. In this regard, the simple synthesis of acyclic diene building blocks embodying an α-amino acid moiety has been achieved. The diene building blocks have been prepared by cross enyne-metathesis reaction as a key step. The Diels-Alder reaction of the dienes with a dienophile such as dimethyl acetylenedicarboxilate (DMAD) followed by oxidation of the resulting cycloadduct gave highly substituted phenylalanine derivatives.
Synthesis of unusual α-amino acid derivatives via cross-enyne metathesis reaction
Kotha, Sambasivarao,Halder, Somnath,Brahmachary, Enugurthi,Ganesh, Thota
, p. 853 - 855 (2007/10/03)
Various highly functionalized phenylalanine derivatives are prepared via cross-enyne metathesis and Diels-Alder reaction as key steps.
