2326-78-5

Usage

Uses

Used in Coordination Chemistry:
[2,2'-Bipyridine]-5,5'-diol is used as a ligand for forming stable coordination complexes with metal ions. Its ability to chelate with metals enhances the stability and reactivity of the resulting complexes, which is crucial in various chemical reactions and processes.
Used in Catalysis:
In the field of catalysis, [2,2'-Bipyridine]-5,5'-diol is employed as a ligand in the development of homogeneous and heterogeneous catalysts. Its coordination with metal ions can improve the catalytic activity and selectivity of the catalysts, facilitating various chemical transformations.
Used in Materials Science:
[2,2'-Bipyridine]-5,5'-diol is utilized as a building block in the synthesis of functional materials with tailored properties. Its incorporation into materials can lead to the development of new materials with improved performance in areas such as conductivity, magnetism, and optical properties.
Used in Synthesis of Molecular Structures:
[2,2'-Bipyridine]-5,5'-diol is used as a versatile component in the synthesis of complex molecular structures. Its ability to form stable coordination complexes with metal ions allows for the creation of intricate architectures with potential applications in supramolecular chemistry and molecular recognition.

Upstream product

• 105170-27-2 2-bromo-5-methoxypyridine 
• 39858-87-2 5,5′-dimethoxy-2,2′-bipyridine 

Relevant academic research and scientific papers

Synthesis of heteroleptic phosphine-copper(i) complexes: Fluorescence sensing and catalytic properties

Heteroleptic copper(i)-phosphine complexes have attracted considerable attention because of their diverse structures, and photophysical and catalytic properties. In this work, a series of heteroleptic diimine-diphosphine Cu(i) complexes (C1-C10) were synthesized quantitively using the designed bipyridine (L1-L4) and bidentate polyphosphine (L5-L8) as functional ligands. These mixed ligand-copper(i) complexes were fully characterized by 1H and 13C NMR spectroscopy, electrospray ionization mass spectrometry (ESI-MS) and elemental analysis. The detailed structures of complexes C1, C2, C5, C6, C9 and C10 were confirmed by single-crystal X-ray diffraction analysis. Moreover, these phosphine-Cu(i) complexes exhibited intense emissions either in the solid state or in solution under UV light excitation. The emissive complexes C1-C4 displayed highly sensitive luminescence sensing towards silver ions in a quenching fashion (turn-off). Furthermore, all the phosphine-protected copper(i) complexes exhibited high catalytic activity towards azide-alkyne cycloaddition (CuAAC) in water.

Novel seco cyclopropa[c]pyrrolo[3,2-e]indole bisalkylators bearing a 3,3′-arylenebisacryloyl group as a linker

We synthesized the novel seco cyclopropa[c]pyrrolo[3,2-e]indole (CPI) bisalkylators and evaluated their antitumor activity. Among these derivatives, 11a (AT-760), in which the two seco 3-methoxycarbonyl-2-trifluoromethyl CPI (MCTFCPI) moieties are connected with a 3,3′-(1,4-phenylene)bisacryloyl group, was found to exhibit more potent cytotoxicity and antitumor activity against HeLaS3 human uterine cervix carcinoma cells and Colon 26 adenocarcinoma cells, respectively, than 8 (bizelesin, U-77,779). It also appeared that compound 11a exhibits improved in vivo efficacy in the human colon CX-1 model when compared to either compound 8 or mitomycin C (MMC). Efficacious doses for 11a were found to be 2-fold lower than those for 8.