23282-87-3Relevant academic research and scientific papers
Design and Synthesis of 1,3,4-Thiadiazole Derivatives as Novel Anticancer and Antitubercular Agents
Chandra Sekhar,Venkata Rao,Tejeswara Rao,Lav Kumar,Jha, Anjali
, p. 770 - 779 (2019/06/05)
A series of novel 5-phenyl-substituted 1,3,4-thiadiazole-2-amines were designed, synthesized, and screened for their antitumor and antitubercular activities. The target compounds were synthesized starting from isocyanates and acid hydrazides by convention
Dithiocarbamate as an efficient intermediate for the synthesis of 2-amino-1,3,4-thiadiazoles in water
Aryanasab, Fezzeh,Halimehjani, Azim Ziyaei,Saidi, Mohammad R.
supporting information; experimental part, p. 790 - 792 (2010/03/24)
A new and facile protocol for the synthesis of 2-amino-1,3,4-thiadiazoles in water is described. Reaction of acid hydrazides with easily prepared dithiocarbamates gives the corresponding thiadiazoles in moderate to excellent yields. 2-Amino-1,3,4-oxadiazoles were not observed as side products using this procedure.
