233253-70-8

Upstream product

• 643-79-8 o-phthalic dicarboxaldehyde 
• 139086-86-5 2-(1,3-dioxan-2-yl)benzaldehyde 
• 233253-68-4 [2-(1,3-dioxan-2-yl)phenyl]ethene 

Downstream Products

• 320600-37-1 (R)-1-O-Benzoyl-2-[2-(1,3-dioxan-2-yl)phenyl]ethane-1,2-diol 
• 459831-00-6 (R)-1-O-pivaloyl-1-(2-(1,3-dioxan-2-yl)phenyl)ethan-1,2-diol 
• 320600-42-8 (1'R,3'R)-1-(3'-benzoyloxymethyl-1',3'-dihydrobenzo[c]furan-1-yl)uracil 
• 320600-44-0 (1'S,3'R)-1-(3'-benzoyloxymethyl-1',3'-dihydrobenzo[c]furan-1-yl)uracil 
• 233253-72-0 (1R,3R)-3-Benzoyloxymethyl-1,3-dihydro-1-methoxybenzo[c]furan 
• 847830-61-9 Benzoic acid (R)-3-hydroxy-1,3-dihydro-isobenzofuran-1-ylmethyl ester 

Relevant academic research and scientific papers

Simple and stereoselective syntheses of nucleoside analogues with a benzo[c]furan glycone moiety

A series of d4T analogues have been synthesised in which the 2',3'- didehydro-2',3'-dideoxyribose moiety is replaced by a benzo[c]furan core. A simple strategy has been developed to access a range of compounds for biological screening. In addition, a ster

Enantiomerical excess determination, purification and biological evaluation of (3S) and (3R) α,β-butenolide analogues of isobenzofuranone

The asymmetric synthesis of isobenzofurane analogues, new potential antiviral agents, is reported. High performance liquid chromatography (HPLC) was the technique chosen to separate the enantiomers. We describe this chiral separation and then determine th

Enantiomeric d4T analogues and their structural determination

Asymmetric synthesis of d4T analogues having a benzo[c]furan moiety with two asymmetric carbon atoms was realized using Sharpless asymmetric dihydroxylation as the key step in a synthesis starting from o-phthalaldehyde. Enantiomeric purities were determin

Stereoisomeric pyrimidine nucleoside analogues based on the 1,3-dihydrobenzo[c]furan core

Stereoisomeric pyrimidine nucleoside analogues based on the 1,3-dihydrobenzo[c]furan core was described. The overall yield of 3-benzoyloxymethyl-1,3-dihydro-1-methoxybenzo[c]furan from aldehyde was 42%. After removal of the protecting group the four stere