233266-78-9 Usage
Uses
Used in Pharmaceutical Industry:
3,5-di-O-benzyl-4-C-ethynyl-1,2-O-isopropylidene-D-ribo-pentofuranose is used as a synthetic intermediate for the development of novel pharmaceutical compounds. Its unique structural features make it a valuable building block in the synthesis of complex molecules with potential therapeutic applications.
Used in Chemical Research:
In the field of chemical research, 3,5-di-O-benzyl-4-C-ethynyl-1,2-O-isopropylidene-D-ribo-pentofuranose serves as a key compound for studying the reactivity and functionalization of pentofuranose derivatives. Its unique structural elements allow researchers to explore new reaction pathways and develop innovative synthetic strategies.
Used in Synthesis of Nucleoside Compounds:
3,5-di-O-benzyl-4-C-ethynyl-1,2-O-isopropylidene-D-ribo-pentofuranose is used as a reagent in the synthesis of novel nucleoside compounds that display anti-HIV activity. Its unique structural features enable the development of new nucleoside analogs with potential antiviral properties, contributing to the fight against HIV and other viral infections.
Check Digit Verification of cas no
The CAS Registry Mumber 233266-78-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,3,3,2,6 and 6 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 233266-78:
(8*2)+(7*3)+(6*3)+(5*2)+(4*6)+(3*6)+(2*7)+(1*8)=129
129 % 10 = 9
So 233266-78-9 is a valid CAS Registry Number.
233266-78-9Relevant articles and documents
4′-C-ethynyl pyrimidine nucleoside compounds and pharmaceutical compositions
-
, (2008/06/13)
The invention provides 4′-C-ethynyl pyrimidine nucleosides (other than 4′-C-ethynylthymidine) represented by formula [I]: wherein B represents a base selected from the group consisting of pyrimidine and derivatives thereof; X represents a hydrogen atom or
Syntheses of 4'-C-ethynyl-beta-D-arabino- and 4'-C-ethynyl-2'-deoxy-beta-D-ribo-pentofuranosylpyrimidines and -purines and evaluation of their anti-HIV activity.
Ohrui,Kohgo,Kitano,Sakata,Kodama,Yoshimura,Matsuoka,Shigeta,Mitsuya
, p. 4516 - 4525 (2007/10/03)
4'-C-Ethynyl-beta-D-arabino- and 4'-C-ethynyl-2'-deoxy-beta-D-ribo-pentofuranosylpyrimidine and -purine nucleosides were synthesized and evaluated for their in vitro anti-HIV activity. The key intermediate, 4-C-ethynyl- or 4-C-triethylsilylethynyl-D-ribo-
Synthesis of 4'-C-ethynyl-beta-D-arabino- and 4'-C-ethynyl-2'-deoxy-beta- D-ribo-pentofuranosyl pyrimidines, and their biological evaluation.
Kohgo,Horie,Ohrui
, p. 1146 - 1149 (2007/10/03)
4'-C-Ethynyl-beta-D-arabino-pentofuranosyl thymine (14) and cytosine (16), and 4'-C-ethynyl-2'-deoxy-beta-D-ribo-pentofuranosyl thymine (25) and cytosine (27) were synthesized by properly protected 4'-C-hydroxy-methyl-3,5-di-O-benzyl-alpha-D-ribo-pentofur