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3,5-di-O-benzyl-4-C-ethynyl-1,2-O-isopropylidene-D-ribo-pentofuranose is a complex organic compound that belongs to the class of pentofuranoses, which are five-carbon sugar derivatives. It is characterized by its unique structural features, including benzyl groups at the 3 and 5 positions, an ethynyl group at the 4 position, and an isopropylidene group bridging the 1 and 2 positions. 3,5-di-O-benzyl-4-C-ethynyl-1,2-O-isopropylidene-D-ribo-pentofuranose is synthesized for various applications in the field of organic chemistry, particularly in the synthesis of complex molecules and pharmaceuticals.

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  • (3aR,5R,6S,6aR)-6-(benzyloxy)-5-((benzyloxy)methyl)-5-ethynyl-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole

    Cas No: 233266-78-9

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  • (3aR,5R,6S,6aR)-6-(benzyloxy)-5-[(benzyloxy)methyl]-5-ethynyl-2,2-dimethyl-tetrahydro-2H-furo[2,3-d][1,3]dioxole

    Cas No: 233266-78-9

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  • 233266-78-9 Structure
  • Basic information

    1. Product Name: 3,5-di-O-benzyl-4-C-ethynyl-1,2-O-isopropylidene-D-ribo-pentofuranose
    2. Synonyms: 3,5-di-O-benzyl-4-C-ethynyl-1,2-O-isopropylidene-D-ribo-pentofuranose
    3. CAS NO:233266-78-9
    4. Molecular Formula:
    5. Molecular Weight: 394.467
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 233266-78-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 486.6±45.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: 1.20±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3,5-di-O-benzyl-4-C-ethynyl-1,2-O-isopropylidene-D-ribo-pentofuranose(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3,5-di-O-benzyl-4-C-ethynyl-1,2-O-isopropylidene-D-ribo-pentofuranose(233266-78-9)
    11. EPA Substance Registry System: 3,5-di-O-benzyl-4-C-ethynyl-1,2-O-isopropylidene-D-ribo-pentofuranose(233266-78-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 233266-78-9(Hazardous Substances Data)

233266-78-9 Usage

Uses

Used in Pharmaceutical Industry:
3,5-di-O-benzyl-4-C-ethynyl-1,2-O-isopropylidene-D-ribo-pentofuranose is used as a synthetic intermediate for the development of novel pharmaceutical compounds. Its unique structural features make it a valuable building block in the synthesis of complex molecules with potential therapeutic applications.
Used in Chemical Research:
In the field of chemical research, 3,5-di-O-benzyl-4-C-ethynyl-1,2-O-isopropylidene-D-ribo-pentofuranose serves as a key compound for studying the reactivity and functionalization of pentofuranose derivatives. Its unique structural elements allow researchers to explore new reaction pathways and develop innovative synthetic strategies.
Used in Synthesis of Nucleoside Compounds:
3,5-di-O-benzyl-4-C-ethynyl-1,2-O-isopropylidene-D-ribo-pentofuranose is used as a reagent in the synthesis of novel nucleoside compounds that display anti-HIV activity. Its unique structural features enable the development of new nucleoside analogs with potential antiviral properties, contributing to the fight against HIV and other viral infections.

Check Digit Verification of cas no

The CAS Registry Mumber 233266-78-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,3,3,2,6 and 6 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 233266-78:
(8*2)+(7*3)+(6*3)+(5*2)+(4*6)+(3*6)+(2*7)+(1*8)=129
129 % 10 = 9
So 233266-78-9 is a valid CAS Registry Number.

233266-78-9Relevant articles and documents

4′-C-ethynyl pyrimidine nucleoside compounds and pharmaceutical compositions

-

, (2008/06/13)

The invention provides 4′-C-ethynyl pyrimidine nucleosides (other than 4′-C-ethynylthymidine) represented by formula [I]: wherein B represents a base selected from the group consisting of pyrimidine and derivatives thereof; X represents a hydrogen atom or

Syntheses of 4'-C-ethynyl-beta-D-arabino- and 4'-C-ethynyl-2'-deoxy-beta-D-ribo-pentofuranosylpyrimidines and -purines and evaluation of their anti-HIV activity.

Ohrui,Kohgo,Kitano,Sakata,Kodama,Yoshimura,Matsuoka,Shigeta,Mitsuya

, p. 4516 - 4525 (2007/10/03)

4'-C-Ethynyl-beta-D-arabino- and 4'-C-ethynyl-2'-deoxy-beta-D-ribo-pentofuranosylpyrimidine and -purine nucleosides were synthesized and evaluated for their in vitro anti-HIV activity. The key intermediate, 4-C-ethynyl- or 4-C-triethylsilylethynyl-D-ribo-

Synthesis of 4'-C-ethynyl-beta-D-arabino- and 4'-C-ethynyl-2'-deoxy-beta- D-ribo-pentofuranosyl pyrimidines, and their biological evaluation.

Kohgo,Horie,Ohrui

, p. 1146 - 1149 (2007/10/03)

4'-C-Ethynyl-beta-D-arabino-pentofuranosyl thymine (14) and cytosine (16), and 4'-C-ethynyl-2'-deoxy-beta-D-ribo-pentofuranosyl thymine (25) and cytosine (27) were synthesized by properly protected 4'-C-hydroxy-methyl-3,5-di-O-benzyl-alpha-D-ribo-pentofur

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