23327-19-7

Upstream product

• 646-07-1 4-Methylpentanoic acid 
• 3123-97-5 dihydro-5,5-dimethyl-2(3H)-furanone 
• 7732-18-5 water 

Downstream Products

• 3123-97-5 dihydro-5,5-dimethyl-2(3H)-furanone 
• 7732-18-5 water 
• 383397-41-9 (2R)-(+)-4-triethylsilyloxy-4-methyl-2-(phenylmethoxycarbonyloxy)pentanoic acid 
• 383397-33-9 (4R,5S)-(+)-4-methyl-5-phenyl-3-[4-triethylsilyloxy-4-methylpentanoyl]-2-oxazolidinone 
• 383397-36-2 (4R,5S,2'R)-(+)-4-methyl-5-phenyl-3-[2-hydroxy-4-triethylsilyloxy-4-methylpentanoyl]-2-oxazolidinone 
• 383397-45-3 (S)-1-((R)-2-Benzyloxycarbonyloxy-4-methyl-4-triethylsilanyloxy-pentanoyl)-pyrrolidine-2-carboxylic acid 
• 383397-38-4 Carbonic acid benzyl ester (R)-3-methyl-1-((4R,5S)-4-methyl-2-oxo-5-phenyl-oxazolidine-3-carbonyl)-3-triethylsilanyloxy-butyl ester 
• 383397-43-1 (S)-1-((R)-2-Benzyloxycarbonyloxy-4-methyl-4-triethylsilanyloxy-pentanoyl)-pyrrolidine-2-carboxylic acid allyl ester 
• 383397-40-8 3-tert-Butoxycarbonylamino-propionic acid (R)-3-methyl-1-((4R,5S)-4-methyl-2-oxo-5-phenyl-oxazolidine-3-carbonyl)-3-triethylsilanyloxy-butyl ester 
• 383397-42-0 (S)-1-[(R)-2-(3-tert-Butoxycarbonylamino-propionyloxy)-4-methyl-4-triethylsilanyloxy-pentanoyl]-pyrrolidine-2-carboxylic acid benzyl ester 
• 383397-22-6 carbonic acid benzyl ester 1-(2-{1-[(1-{[2-(N'-tert-butoxycarbonyl-hydrazino)-1-methyl-2-oxo-ethyl]-methyl-carbamoyl}-2-methyl-propyl)-methyl-carbamoyl]-2-methyl-butylcarbamoyl}-pyrrolidine-1-carbonyl)-3-methyl-3-triethylsilanyloxy-butyl ester 

Relevant academic research and scientific papers

An iron catalyst for oxidation of alkyl C-H bonds showing enhanced selectivity for methylenic sites

Many are called but few are chosen: A nonheme iron complex catalyzes the oxidation of alkyl C-H bonds by using H2O2 as the oxidant, showing an enhanced selectivity for secondary over tertiary C-H bonds (see scheme). Copyright

Probing host-selective phytotoxicity: Synthesis of destruxin B and several natural analogues

The syntheses of the host-selective phytotoxin destruxin B [cyclo(βAla-Hmp-Pro-Ile-MeVal-MeAla), Hmp = (2R)-2-hydroxy-4-methylpentanoic acid], and the closely related natural analogues homodestruxin B (MeVal→MeIle), desmethyldestruxin B (MeVal→Val), hydroxydestruxin B (Hmp→Dhmp, Dhmp = (2R)-2,4-dihydroxy-4-methylpentanoic acid), and hydroxyhomodestruxin B (MeVal→MeIle, Hmp→Dhmp) are described. In each case, the MeAla-βAla linkage was formed by cyclization and the precursor linear hexadepsipeptides were formed by condensing two three-residue fragments. Radiolabeled samples of destruxin B, homodestruxin B, and hydroxydestruxin B were prepared by coupling [3-14C]-β-alanine to the appropriate pentadepsipeptide followed by cyclization. A noteworthy feature of the synthesis involves the novel use of a Boc-hydrazide protecting group on dipeptides with a C-terminal N-methylalanine residue to inhibit the otherwise facile dioxopiperazine formation during peptide coupling.