233277-16-2Relevant academic research and scientific papers
Lipase mediated preparation of differently protected homochiral 2-aryl- 2-fluoro-1,3-propanediols
Guanti, Giuseppe,Narisano, Enrica,Riva, Renata
, p. 1859 - 1862 (1998)
Lipase mediated asymmetric monohydrolysis of 2-aryl-2-fluoromalonic acid diesters or monoacetylation of 2-aryl-2-fluoro-1,3-propanediols affords chiral fiuorinated polyfunctionalized C3 synthons in excellent enantiomeric excess and acceptable chemical yields.
Chemoenzymatic synthesis of 2-substituted 2-fluoro-1,3-dioxygenated chiral building blocks
Narisano, Enrica,Riva, Renata
, p. 1223 - 1242 (2007/10/03)
A series of 2-substituted-2-fluoro-1,3-dioxygenated chiral building blocks are synthesized via a chemoenzymatic route using either (i) lipase catalyzed monohydrolysis of suitably functionalized malonic diesters, or (ii) lipase catalyzed monoacetylation of suitably functionalized 1,3-propanediols.
