233584-99-1Relevant academic research and scientific papers
Synthesis of symmetric bis(imidazole-4,5-dicarboxamides) substituted with amino acids
Wiznycia, Alexander V.,Rush, Jeremy R.,Baures, Paul W.
, p. 8489 - 8491 (2007/10/03)
A series of symmetric bis(imidazole-4,5-dicarboxamides) (bis-I45DCs) were prepared with amino acid esters and a variety of linker groups. The critical pyrazine intermediates, substituted with amino acid esters, were synthesized by stoichiometric control o
Heterocyclic HIV-1 protease inhibitors.
Baures
, p. 249 - 252 (2008/02/13)
[formula: see text] A series of simple heterocyclic HIV-1 protease inhibitors were developed on the basis of size, shape, and electronic complementarity to the active site of the enzyme. The C2-symmetric heterocycles do not contain a transition-state isos
