570-22-9

Basic information

• Product Name: 4,5-Imidazoledicarboxylic acid
• Synonyms: IMIDAZOLE-4,5-DICARBOXYLIC ACID;IFLAB-BB F1918-0019;AKOS BBS-00002898;AKOS AUF2071;4,5-IMIDAZOLEDICARBOXYLIC ACID;1H-IMIDAZOLE-4,5-DICARBOXYLIC ACID;RARECHEM AL BO 1102;,-Imidazoledicarboxylicacid
• CAS NO: 570-22-9
• Molecular Formula: C₅H₄N₂O₄
• Molecular Weight: 156.1
• EINECS: 209-327-5
• Product Categories: Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines;Imidazol&Benzimidazole;Heterocyclic Compounds;Imidaxoles;Alcohols;Monomers;Polymer Science;Building Blocks;Heterocyclic Building Blocks;Imidazoles
• Mol File: 570-22-9.mol
• Article Data: 8

Chemical Properties

• Melting Point: 280-285 °C (dec.)(lit.)
• Boiling Point: 280.29°C (rough estimate)
• Flash Point: 335.5 °C
• Appearance: Light yellow to yellow-brown/Fine Crystalline Powder
• Density: 1,749 g/cm3
• Vapor Pressure: 8.51E-17mmHg at 25°C
• Refractive Index: 1.4800 (estimate)
• Storage Temp.: Store below +30°C.
• Solubility: 0.5g/l
• PKA: 3.59±0.10(Predicted)
• Water Solubility: 0.5g/L(20 oC)
• BRN: 147774
• CAS DataBase Reference: 4,5-Imidazoledicarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-Imidazoledicarboxylic acid(570-22-9)
• EPA Substance Registry System: 4,5-Imidazoledicarboxylic acid(570-22-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-37/39
• WGK Germany: 3
• RTECS: NI4760000
• TSCA: Yes
• Hazardous Substances Data: 570-22-9(Hazardous Substances Data)

Usage

Chemical Properties

light yellow to yellow-brown fine cryst. powder

Uses

Different sources of media describe the Uses of 570-22-9 differently. You can refer to the following data:
1. 4,5-Imidazoledicarboxylic acid is an imidazole used for research purposes.
2. 4,5-Imidazoledicarboxylic Acid is an intermediate used in the synthesis of N-substituted cyclic imides with anticancer and anti-inflammatory activities. it is also used to prepare imidazolecarboxamide derivatives with cannabinoid CB2 receptor antagonistic activities.

InChI:InChI=1/C5H4N2O4/c8-4(9)2-3(5(10)11)7-1-6-2/h1H,(H,6,7)(H,8,9)(H,10,11)/p-2

Upstream product

• 50-00-0 formaldehyd 
• 13171-63-6 L_g-tartaric acid-dinitrate 
• 51-17-2 benzoimidazole 
• 288-32-4 1H-imidazole 
• 5465-29-2 2-propyl-1H-benzimidazole 
• 716-79-0 2-phenyl-1H-benzoimidazole 
• 1848-84-6 2-ethylbenzimidazole 
• 615-15-6 2-Methyl-1H-benzimidazole 
• 125029-71-2 2,4,5-Tris(dimethylaminomethyl)imidazole Trihydrochloride 
• 125029-70-1 5-Dimethylaminomethylimidazole-4-carboxylic Acid Hydrochloride 
• 1122-28-7 4,5-dicyano-1H-imidazole 
• 100-97-0 hexamethylenetetramine 
• 874000-31-4 1H-cyclohePtimidazol-6-one-imine 

Downstream Products

• 5467-45-8 2-Phenylazo-1H-imidazole-4,5-dicarboxylic acid 
• 26832-08-6 imidazole-4-carboxamide 
• 59157-06-1 4H,9H-diimidazo<1,5-a; 1',5'-d>pyrazine-5,10-dione-1,6-dicarboxylic dichloride 
• 59399-36-9 imidazole-4,5-dicarboxylic acid chloride 
• 773099-17-5 2-bromo-1H-imidazole-4,5-dicarboxylic acid 
• 1210-92-0 diethyl 1-methylimidazol-1H-yl-4,5-dicarboxylate 

Relevant articles and documents

Synthesis, structure, and photoluminescent property of a trinuclear Cd II complex based on semi-rigid bis(imidazole-4,5-dicarboxylate) ligand

A new 3D complex, {[Cd3(HL)2(H2L)(H 2O)4]·2H2O}n (1) (H 4L = 1,1′-(1,4-phenylenebis(methylene))bis(1H-imidazole-4,5- dicarboxylic acid), has been hydrothermally synthesized and characterized by elemental analyses, IR, TG, and X-ray single-crystal diffraction. Complex 1 is the first framework based on CdII ion and semi-rigid bis-IDC ligand. The (6,6)-net architecture of 1 is built from H2L2 - ligands linking 1D chain-like [Cd3(HL)2]n SBUs, which formed by HL3 - anions bridging two kinds of metal centers. In addition, complex 1 was demonstrated to display strong blue-violet fluorescence emission in the solid state at room temperature.

Olmesartan high purity intermediate 2-propyl imidazole -4,5-dicarboxylic acid preparation method and application

The invention provides a preparation method of 2-propylimidazolyl-4,5-dicarboxylic acid (1). According to the method, the concentration of the sulfuric acid solution, the volume/mass ratio of the sulfuric acid solution to 2-propyl benzimidazole, the volume ratio of the oxydol to the sulfuric acid water solution, reaction time, added water volume and cooling recrystallization temperature are accurately controlled to obviously lower the content of the impurity imidazolyl-4,5-dicarboxylic acid (8), thereby further obtaining the high-purity olmesartan medoxomil. The invention also provides a compound disclosed as Formula 9 and application thereof in olmesartan medoxomil preparation as a control quality standard substance.

Reactions of ozone with heteroarenes

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