233606-12-7

Upstream product

• 135691-02-0 N-(2-Hydroxyethyl)-2-methoxy-6-methylbenzamide 
• 6161-65-5 2-methoxy-6-methyl-benzoic acid 
• 50463-84-8 2-methoxy-6-methylbenzoyl chloride 

Downstream Products

• 135691-03-1 4,5-Dihydro-2-(2-methoxy-6-methylphenyl)oxazole 
• 135691-04-2 ((S)-1-{1-[(Z)-2-Hydroxy-ethylimino]-8-methoxy-isochroman-3-yl}-3-methyl-butyl)-carbamic acid benzyl ester 
• 135691-06-4 (1'S,3S)-3-(1-Benzyloxycarbonylamino-3-methylbutyl)-3,4-dihydro-8-methoxy-1H-2-benzopyran-1-one 
• 135691-07-5 (1'R,3S)-3-(1-Benzyloxycarbonylamino-3-methylbutyl)-3,4-dihydro-8-methoxy-1H-2-benzopyran-1-one 
• 135691-05-3 ((S)-1-{2-[2-(4,5-Dihydro-oxazol-2-yl)-3-methoxy-phenyl]-1-hydroxy-ethyl}-3-methyl-butyl)-carbamic acid benzyl ester 
• 135691-08-6 (1'S,3S)-3-(1-Benzyloxycarbonylamino-3-methylbutyl)-3,4-dihydro-8-hydroxy-1H-2-benzopyran-1-one 

Relevant academic research and scientific papers

Total synthesis method of hetiamacin A

The invention relates to a total synthesis method of hetiamacin A. The method comprises the steps as follows: a compound (S)-3-((S)-1-amino-3-methylbutyl)-8-hydroxy 3,4-dibydro-isobenzopyran-1-ketone and a compound (2S,3S,4S)-2-amino-4-(carbobenzoxy amino

Total synthesis of AI-77-B: Stereoselective hydroxylation of 4-alkenylazetidinones

A stereoselective synthesis of the anti-ulcer compound AI-77-B 1 is described. The 4-formylazetidinone 6 was converted into the 4-(Z)-alkene 23 using a phosphonate condensation, and dihydroxylation using osmium tetroxide and N-methylmorpholine W-oxide gav

Total Synthesis of Al-77-B

Stereoselective hydroxylation of the β-lactam ester 8 is a key step in a total synthesis of Al-77-B 1.