233676-40-9Relevant academic research and scientific papers
Synthesis of water-Soluble prodrugs of BMS-191011: A maxi-K channel opener targeted for post-stroke neuroprotection
Hewawasam, Piyasena,Ding, Min,Chen, Nathan,King, Dalton,Knipe, Jay,Pajor, Lorraine,Ortiz, Astrid,Gribkoff, Valentin K.,Starrett, John
, p. 1695 - 1698 (2003)
A variety of water-soluble prodrugs of BMS-191011 was synthesized and evaluated for solution state stability and rate of conversion to BMS-191011 in rat and human plasma. The deoxycarnitine ester prodrug (11c) was selected for clinical evaluation based on
PHOSPHATE DERIVATIVES OF DIARYL 1,3,4-OXADIAZOLONE
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, (2008/06/13)
The present invention provides novel phosphate derivatives having the general formula wherein A, R1 and R2 are as defined herein, or a nontoxic pharmaceutically acceptable salt or solvate thereof and are useful in the treatment of disorders which are resp
PHOSPHATE DERIVATIVES OF DIARYL 1,3,4-OXADIAZOLONE
-
, (2008/06/13)
The present invention provides novel phosphate derivatives having the general formula wherein A, R 1 and R 2 are as defined herein, or a nontoxic pharmaceutically acceptable salt or solvate thereof and are useful in the treatment of disorders which are re
