23384-06-7Relevant academic research and scientific papers
Meta Selective C-H Borylation of Sterically Biased and Unbiased Substrates Directed by Electrostatic Interaction
Chaturvedi, Jagriti,Haldar, Chabush,Bisht, Ranjana,Pandey, Gajanan,Chattopadhyay, Buddhadeb
supporting information, p. 7604 - 7611 (2021/05/26)
An electrostatically directed meta borylation of sterically biased and unbiased substrates is described. The borylation follows an electrostatic interaction between the partially positive and negative charges between the ligand and substrate. With this strategy, it has been demonstrated that a wide number of challenging substrates, especially 4-substituted substrates, can selectively be borylated at the meta position. Moreover, unsubstituted substrates also displayed excellent meta selectivity. The reaction employs a bench-stable ligand and proceeds at a milder temperature, precluding the need to synthesize a bulky and sophisticated ligand/template.
Diamination of Domino Aryne Precursor with Sulfonamides
Qiu, Dachuan,He, Jia,Yue, Xiao,Shi, Jiarong,Li, Yang
supporting information, p. 3130 - 3133 (2016/07/14)
The reaction of a domino aryne precursor with sulfonamides efficiently afforded both 1,3-diaminobenzenes and trisubstituted 1,3-diaminobenzenes by simply varying the reaction conditions. Mechanistic study supports the sequential formation of two transient aryne intermediates involved in the reaction.
Substituted benzyl pyrimidines
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, (2008/06/13)
Compounds of the formula: STR1 in which R1 is lower alkoxy, R2 is bromine or lower alkoxy, and R3 is aryl, heteroaryl or a group --Q--R30, wherein Q is ethylene, vinylene or ethynylene and R30 is aryl, heteroaryl, lower alkoxycarbonyl or carbamoyl; hydrolyzable esters of carboxylic acids of formula I; and pharmaceutically acceptable salts of these compounds are useful for treating infectious diseases.
