23384-22-7 Usage
Uses
Used in Organic Synthesis:
N-(2,4-difluorophenyl)-1,1,1-trifluoroMethane sulfonaMide is used as a reagent in organic synthesis for its strong electron-withdrawing properties, which are beneficial in reactions involving aromatic compounds.
Used in Pharmaceutical Research:
In pharmaceutical research, N-(2,4-difluorophenyl)-1,1,1-trifluoroMethane sulfonaMide is utilized as a building block in the synthesis of various pharmaceutical intermediates, contributing to the development of new medications.
Used in Agrochemicals:
N-(2,4-difluorophenyl)-1,1,1-trifluoroMethane sulfonaMide is also used in the synthesis of agrochemicals, where its properties can be leveraged to create effective products for agricultural applications.
Used in Antiviral and Antimicrobial Research:
N-(2,4-difluorophenyl)-1,1,1-trifluoroMethane sulfonaMide is being studied for its potential as an antiviral and antimicrobial agent, indicating its possible use in the development of treatments for viral and bacterial infections.
Check Digit Verification of cas no
The CAS Registry Mumber 23384-22-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,3,8 and 4 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 23384-22:
(7*2)+(6*3)+(5*3)+(4*8)+(3*4)+(2*2)+(1*2)=97
97 % 10 = 7
So 23384-22-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H4F5NO2S/c8-4-1-2-6(5(9)3-4)13-16(14,15)7(10,11)12/h1-3,13H
23384-22-7Relevant academic research and scientific papers
Fluorination of Aromatic Derivatives with Fluoroxytrifluoromethane and Bis(fluoroxy)difluoromethane
Fifolt, Michael J.,Olczak, Raymond T.,Mundhenke, Rudolph F.
, p. 4576 - 4582 (2007/10/02)
Fluoroxytrifluoromethane (CF3OF) and bis(fluoroxy)difluoromethane CF2(OF)2 are formed by the reaction of F2 with CO and CO2, respectively, over a CsF catalyst in a continouous-stream process.Both reagents react with aromatic substrates by an electrophilic substitution mechanism to yield fluoro-substituted derivatives.Fluorobenzene is produced in good yield from benzene, and aniline derivatives afford monofluorination products.Acetanilide (1), N-phenylmethanesulfonamide (2), α,α,α-trifluoroacetanilide (3), and 1,1,1-trifluoro(N-phenyl)methanesulfonamide (4) react with either reagent to yield mixtures of o- and p-fluoro-substituted derivatives.Solvent effects and competitive rate experiments demonstrate a preference for ortho substitution, especially in aprotic, nonpolar solvents.With particular substrates, these fluorinating agents are of practical synthetic utility, e.g., 2-fluoro-4-(trifluoromethyl)aniline is produced in high yield by fluorinating the intermediate 4-(trifluoromethyl)acetanilide (6) with CF3OF.Activated substrates such as toluene, xylenes, anisole, and cresols give mixtures of products which reduce the synthetic utility of these reagents.Nitrobenzene is fairly unreactive toward CF3OF and gives low yields of substitution products.
