23389-76-6

Basic information

• Product Name: 4-Pyridinemethanol, a-ethyl-
• CAS NO: 23389-76-6
• Molecular Formula: C8H11NO
• Molecular Weight: 137.181
• Mol File: 23389-76-6.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 4-Pyridinemethanol, a-ethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyridinemethanol, a-ethyl-(23389-76-6)
• EPA Substance Registry System: 4-Pyridinemethanol, a-ethyl-(23389-76-6)

Safety Data

• Hazardous Substances Data: 23389-76-6(Hazardous Substances Data)

Usage

General Description

4-Pyridinemethanol, alpha-ethyl- is a chemical compound with the molecular formula C8H11NO. It is an aromatic alcohol with a pyridine ring and an ethyl group attached to the alpha position. This chemical is used in the synthesis of pharmaceuticals and agrochemicals, as well as in the production of organic compounds. It is also known to have antifungal and antimicrobial properties, making it useful in the development of new drugs and antimicrobial agents. Additionally, it is utilized in various organic reactions and as a building block in the preparation of complex organic molecules. Its unique structure and properties make it a valuable chemical in the field of organic chemistry and drug discovery.

Upstream product

• 62369-32-8 4-(ethoxymethyl)pyridine 
• 91-17-8 decalin 
• 71-43-2 benzene 
• 872-85-5 pyridine-4-carbaldehyde 
• 557-20-0 diethylzinc 
• 1822-51-1 4-picolylchloride hydrochloride 
• 925-90-6 ethylmagnesium bromide 
• 10467-10-4 ethylmagnesium iodide 
• 1122-81-2 4-n-propylpyridine 

Downstream Products

• 17944-59-1 3-(pyridin-4-yl)propyl chloride hydrochloride 
• 1352067-90-3 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-2-oxo-1-((S)-1-(pyridin-4-yl)propyl)piperidin-3-yl)acetic acid 
• 1701-69-5 1-(4-pyridyl)-1-propanone 

Relevant articles and documents

Thermophysical properties of imidazolium-functionalized binols and their application in asymmetric catalysis

We report here the thermophysical properties of a new family of imidazolium-functionalized binaphthols. These properties are influenced by the position of the imidazolium moieties on the binaphthol skeleton, the counteranions, and the length of the carbon chain on the imidazolium moieties. The ionic character of these molecules was also exploited to develop ligands for the catalytic aldehyde ethylation reaction in ionic liquid media. We were able to easily recover both the ionic ligands and the ionic liquid solvent, and the reaction afforded good to excellent yields, with average selectivity.

Turn On of a Ruthenium(II) Photocatalyst by DNA-Templated Ligation

Here, the synthesis of a RuII photocatalyst by light-directed oligonucleotide-templated ligation reaction is described. The photocatalyst was found to have tremendous potential for signal amplification with >15000 turnovers measured in 9 hours. A templated reaction was used to turn on the activity of this ruthenium(II) photocatalyst in response to a specific DNA sequence. The photocatalysis of the ruthenium(II) complex was harnessed to uncage a new precipitating dye that is highly fluorescent and photostable in the solid state. This reaction was used to discriminate between different DNA analytes based on localization of the precipitate as well as for in cellulo miRNA detection. Finally, a bipyridine ligand functionalized with two different peptide nucleic acid (PNA) sequences was shown to enable template-mediated ligation (turn on of the ruthenium(II) photocatalysis) and recruitment of substrate for templated photocatalysis.

Chiral 2-(2-hydroxyaryl)alcohols (HAROLs) with a 1,4-diol scaffold as a new family of ligands and organocatalysts

Efficient and modular syntheses of chiral 2-(2-hydroxyaryl)alcohols (HAROLs), novel 1,4-diols carrying one phenolic and one alcohol hydroxyl group, have been developed which led to generation of a small library of structurally diverse HAROLs in enantiomerically pure form. Of the different HAROLs examined, a HAROL based on the indan backbone exhibited the highest activity and enantioselectivity in the 1,2-addition of certain organometallic compounds to aldehydes in the presence of Ti(OiPr)4 (up to 97% y, 88% ee) and performed as a hydrogen-bond donor organocatalyst in the Morita-Baylis-Hillman reaction, promoted by trialkylphosphines.