2339-57-3

Basic information

• Product Name: o-Toluenesulfonamide, 5-fluoro- (6CI,8CI)
• Synonyms: o-Toluenesulfonamide, 5-fluoro- (6CI,8CI)
• CAS NO: 2339-57-3
• Molecular Formula: C₇H₈FNO₂S
• Molecular Weight: 189.2073232
• Product Categories: SULFONAMIDE
• Mol File: 2339-57-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 334.1 °C at 760 mmHg
• Flash Point: 155.9 °C
• Appearance: /
• Density: 1.362 g/cm³
• Vapor Pressure: 0.00013mmHg at 25°C
• Refractive Index: 1.545
• PKA: 9.96±0.60(Predicted)
• CAS DataBase Reference: o-Toluenesulfonamide, 5-fluoro- (6CI,8CI)(CAS DataBase Reference)
• NIST Chemistry Reference: o-Toluenesulfonamide, 5-fluoro- (6CI,8CI)(2339-57-3)
• EPA Substance Registry System: o-Toluenesulfonamide, 5-fluoro- (6CI,8CI)(2339-57-3)

Safety Data

• Hazardous Substances Data: 2339-57-3(Hazardous Substances Data)

Usage

General Description

o-Toluenesulfonamide, 5-fluoro- (6CI,8CI) is a chemical compound with the molecular formula C7H8FNO2S. It is a sulfonamide derivative containing a fluorine atom, and it is commonly used in the production of pharmaceuticals and agrochemicals. o-Toluenesulfonamide, 5-fluoro- (6CI,8CI) is often used as a building block for the synthesis of various biologically active molecules due to its reactivity and pharmaceutical properties. Additionally, it has been found to have potential antifungal and antibacterial properties, making it a valuable compound in the development of new medications. Overall, o-Toluenesulfonamide, 5-fluoro- (6CI,8CI) is an important chemical with various applications in the pharmaceutical and agricultural industries.

InChI:InChI=1/C7H8FNO2S/c1-5-2-3-6(8)4-7(5)12(9,10)11/h2-4H,1H3,(H2,9,10,11)

Upstream product

• 352-32-9 p-fluorotoluene 
• 445-05-6 5-fluoro-2-methylbenzenesulfonyl chloride 

Downstream Products

• 384-45-2 6-fluoro-1,2-benzisothiazol-3(2H)-one-1,1-dioxide 
• 1254305-50-4 C₁₆H₁₀ClF₄N₃O₃S 

Relevant articles and documents

Discovery of cyclic sulfonamide derivatives as potent inhibitors of SARS-CoV-2

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) continues to spread worldwide, with 25 million confirmed cases and 800 thousand deaths. Effective treatments to target SARS-CoV-2 are urgently needed. In the present study, we have identified a

Substituted N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl} benzamide analogs as potent Kv1.3 ion channel blockers. Part 2

We report the synthesis and in vitro activity of a series of novel substituted N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl} benzamide analogs. These analogs showed potent inhibitory activity against Kv1.3. Several demonstrated similar po

BICYCLIC HETEROCYCLES AS HIV INTEGRASE INHIBITORS

The invention encompasses a series cyclic bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.