445-05-6

Usage

Uses

Used in Pharmaceutical Synthesis:
5-FLUORO-2-METHYLBENZENESULFONYL CHLORIDE is used as a synthetic intermediate for the production of 1-(aminomethyl)-5-fluoro-N,N-dimethyl-benzenesulfonamide. 5-FLUORO-2-METHYLBENZENESULFONYL CHLORIDE serves as a key component in the development of pharmaceuticals, potentially contributing to the creation of new drugs with specific therapeutic applications.
Used in Chemical Research:
As a clear colorless to yellow liquid with unique structural features, 5-FLUORO-2-METHYLBENZENESULFONYL CHLORIDE may also be utilized in chemical research for studying the effects of fluorination and methylation on the reactivity and stability of benzene-based compounds. This can lead to advancements in the understanding of chemical reactions and the development of novel synthetic methods.
Used in Specialty Chemicals:
Due to its specific structural attributes, 5-FLUORO-2-METHYLBENZENESULFONYL CHLORIDE could be employed in the production of specialty chemicals that require tailored properties for particular applications, such as in the fields of materials science, coatings, or advanced polymers.
Used in Analytical Chemistry:
5-FLUORO-2-METHYLBENZENESULFONYL CHLORIDE may also find use in analytical chemistry as a reagent or a reference material for the identification and quantification of related compounds through various analytical techniques, including chromatography and spectroscopy.

InChI:InChI=1/C7H6ClFO2S/c1-5-2-3-6(9)4-7(5)12(8,10)11/h2-4H,1H3

Upstream product

• 352-32-9 p-fluorotoluene 
• 367-29-3 3-fluoro-6-methylaniline 

Downstream Products

• 2339-57-3 5-fluoro-2-methylbenzenesulfonamide 
• 67475-17-6 N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-5-fluoro-2-methyl-benzenesulfonamide 
• 67475-24-5 5-fluoro-2-methyl-N-(5-propyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide 
• 67475-30-3 5-fluoro-N-(5-isopropyl-[1,3,4]thiadiazol-2-yl)-2-methyl-benzenesulfonamide 
• 67475-37-0 N-(5-butyl-[1,3,4]thiadiazol-2-yl)-5-fluoro-2-methyl-benzenesulfonamide 
• 67475-43-8 5-fluoro-N-(5-isobutyl-[1,3,4]thiadiazol-2-yl)-2-methyl-benzenesulfonamide 
• 1827-82-3 5-fluoro-N-[4-(4-fluoro-3-methyl-phenyl)-thiazol-2-yl]-2-methyl-benzenesulfonamide 
• 1765-17-9 5-fluoro-N-[4-(4-fluoro-phenyl)-thiazol-2-yl]-2-methyl-benzenesulfonamide 
• 1827-81-2 5-fluoro-N-[4-(4-fluoro-phenyl)-5-methyl-thiazol-2-yl]-2-methyl-benzenesulfonamide 
• 1525-49-1 5-fluoro-N-[4-(2-fluoro-5-methyl-phenyl)-thiazol-2-yl]-2-methyl-benzenesulfonamide 
• 3833-88-3 N-[5-ethyl-4-(4-fluoro-phenyl)-thiazol-2-yl]-5-fluoro-2-methyl-benzenesulfonamide 
• 82875-73-8 5-Fluoro-2-methyl-benzenesulfonic acid 2-chloro-phenyl ester 
• 116221-95-5 2-phenyl-6-(2-methyl-5-fluorophenyl)-1,3,4-oxadiazolo<3,2-a>-s-triazine-5,7-dithione 
• 116221-96-6 2-p-chlorophenyl-6-(2-methyl-5-fluorophenyl)-1,3,4-oxadiazolo<3,2-a>-s-triazine-5,7-dithione 

Relevant academic research and scientific papers

Quinazolinone Compound and Application Thereof

The present invention relates to a series of quinazolinone compounds and applications thereof as PI3Kα inhibitors. In particular, the present invention relates to a compound shown in formula (I) and a tautomer or pharmaceutically acceptable salt thereof.

Preparation of arylsulfonyl chlorides by chlorosulfonylation of in situ generated diazonium salts using a continuous flow reactor

A new flow procedure for the preparation of arylsulfonyl chlorides from aniline starting materials is described. The reaction conditions are mild, requiring no added acid and are amenable to continuous flow processing, in a safe, easily scalable and less labour intensive way than the corresponding batch method.

Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists

The present invention relates to urotensin II receptor antagonists, CCR-9 antagonists, pharmaceutical compositions containing them and their use.