23391-99-3

Usage

Uses

Used in Organic Synthesis:
4,4'-BICYCLOHEXANONE is utilized as a building block in organic synthesis for the preparation of a range of pharmaceuticals and fine chemicals. Its unique structure and reactivity make it a key intermediate in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4,4'-BICYCLOHEXANONE is used as a starting material for the production of various drugs. Its versatility allows for the creation of different medicinal compounds with potential therapeutic applications.
Used as a Solvent:
4,4'-BICYCLOHEXANONE is employed as a solvent for resins, cellulose ethers, and cellulose acetate. Its solubility properties make it suitable for use in the formulation of various products that require dissolution of these substances.
Used in Adhesives and Coatings Production:
Due to its high boiling point and stability, 4,4'-BICYCLOHEXANONE is used in the production of adhesives and coatings. It contributes to the formulation of these products, enhancing their performance characteristics.
Used in Specialty Chemicals Manufacturing:
4,4'-BICYCLOHEXANONE is a versatile intermediate in the manufacturing of fragrances, flavors, and other specialty chemicals. Its ability to be modified and incorporated into a wide array of chemical products makes it an important component in this industry.

Upstream product

• 20601-38-1 4,4′-dihydroxybicyclohexyl 
• 92-88-6 4,4'-Dihydroxybiphenyl 
• 64554-52-5 1,1'-Bicyclohexylidene-4,4'-dione 
• 101-84-8 diphenylether 
• 46310-14-9 4,4'-e,e-cyclohexylcyclohexanediol 
• 64-19-7 acetic acid 
• 63049-36-5 4',4'-Dimethoxy-4-methylsulfanyl-bicyclohexyl-4-carboxylic acid methyl ester 
• 21326-53-4 sulfur(IV) oxide * pyridine 

Downstream Products

• 109367-22-8 2',3'',2''''',3''''''-tetramethoxy-[1,1';4',1'';4'',1''';4''',1'''';4'''',1''''';4''''',1'''''';4'''''',1''''''']octiphenyl 
• 891828-79-8 4,4'-dimethoxymethylidene bicyclohexane 
• 359414-72-5 Bicyclohexyl-2,2'-diene-4,4'-dione 
• 21470-20-2 3,3'''-Dimethyl-p-quaterphenyl 
• 4499-85-8 2,2'''-dimethyl-p-quaterphenyl 
• 221300-33-0 4-(3,3-dimethyl-1,5-dioxaspiro[5.5]undec-9-yl)cyclohexanone 

Relevant academic research and scientific papers

Photochemical Transformations with Iodine Azide after Release from an Ion-Exchange Resin

This report discloses the photochemical homolytic cleavage of iodine azide after its formation following release from polymer-bound bisazido iodate(I) anions. A series of radical reactions are reported including the 1,2-functionlization of alkenes and the unprecedented chemoselective oxidation of secondary alcohols in the presence of primary alcohols.

A high performance oxidation method for secondary alcohols by inductive activation of TEMPO in combination with pyridine-bromine complexes

A new TEMPO-mediated catalytic oxidation method in combination with Py·HBr3 (stoichiometric) is developed for oxidation of secondary alcohols to the corresponding ketones. The performance of this oxidizing system is better compared with that of TEMPO method combined with R4NBr3. Poly(4-vinylpyridine)·HBr3 can be used in place of Py·HBr3. The electron-withdrawing substituent at the C-4 position of TEMPO increases the reactivity of TEMPO significantly in the oxidation of electron-deficient alcohols such as polyhaloalkylmethanols. Inductive effect of the substituent of TEMPO is discussed through the characterization of the redox potential of N-O radical by cyclic voltammetry.

Process for the preparation of cyclohexanones

The invention relates to a process for the preparation of cyclohexanones from the corresponding phenols by partial hydrogenation, characterized in that the reaction mixture obtained by means of the hydrogenation is treated with sulfonating agents before the isolation of the cyclohexanone.

Oligo(cyclohexylidene) oximes and derivatives as probe molecules for long-range substituent effects on13C NMR chemical shifts

For a series of rodlike aliphatic oximes (1-4) the influence of the oxime substituent on the 13C NMR chemical shifts has been studied. Various 2D NMR techniques were applied for the unequivocal assignment of their 1H and 13C resonances. For bicyclohexylidene oximes 1-2 long-range substituent effects on the 13C NMR chemical shifts of aliphatic carbon atoms of the six-membered rings due to the presence of the oxime group are discernible up to positions six carbon-carbon bonds distant from the iminyl carbon! The 13C NMR data obtained for bicyclohexyl oximes 3-4 reveal that in this series the effect is limited to carbon atoms which are five bonds distant from the iminyl carbon. The observed differences between the two series is attributed to the presence of an olefinic double bond in 1-2, whch becomes polarized by the electric field of the oxime substituent.