23412-22-8

Upstream product

• 6559-91-7 4'-demethylepipodophyllotoxin 
• 501-53-1 benzyl chloroformate 
• 40505-27-9 4-demethylpodophyllotoxin 

Downstream Products

• 93780-84-8 4'-demethylpodophyllotoxone 
• 118190-50-4 (5R,5aR,9S)-9-((1R,2R,3R,4R,5S)-2-Amino-3,4,5-trihydroxy-cyclohexyloxy)-5-(4-hydroxy-3,5-dimethoxy-phenyl)-5,8,8a,9-tetrahydro-5aH-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one 
• 118190-50-4 1-β-<1L-(1,3/2,4,6)-6-amino-1,2,3-trihydroxycyclohexyloxy>-4'-O-demethyl-1-deoxypodophyllotoxin 
• 118190-49-1 (5R,5aR,9S)-9-((1R,2R,3S,4R,5S)-5-Amino-2,3,4-trihydroxy-cyclohexyloxy)-5-(4-hydroxy-3,5-dimethoxy-phenyl)-5,8,8a,9-tetrahydro-5aH-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one 

Relevant academic research and scientific papers

ARYLTETRALIN LIGNANS FROM PODOPHYLLUM HEXANDRUM AND PODOPHYLLUM PELTATUM

Roots of Podophyllum hexandrum and P. peltatum contain the same range of ten aryltetralin lignans: podophyllotoxin, 4'-demethylpodophyllotoxin, α-peltatin, β-peltatin, desoxypodophyllotoxin, podophyllotoxone, isopicropodophyllone, 4'-demetyldesoxypodophyllotoxin, 4'-demethylpodophyllotoxone and 4'-demethylisopicropodophyllone, although the relative proportions are markedly different.The latter two compounds are previously unreported natural products, but 4'-demethylisopicropodophyllone may well be an artefact resulting from epimerization of 4'-demethylpodophyllotoxone.The peltatins have not previously been isolated from P. hexandrum.Key Word Index - Podophyllum hexandrum; P. peltatum; Podophyllaceae; aryltetralin; lignans; podophyllotoxin.

ORGANOPLATINUM COMPOUNDS AND PHARMACEUTICAL COMPOSITION THEREOF AND METHOD OF PREPARING CRYSTAL OF hTop2

Some organoplatinum compounds have been synthesized. These organoplatinum compounds are designed to be human Topoisomerase II-targeting drugs.

HUMAN TOPOISOMERASE II-TARGETING ORGANOPLATINUM COMPOUNDS

Some organoplatinum compounds have been synthesized. These organoplatinum compounds are designed to be human Topoisomerase II-targeting drugs.