23434-03-9

Upstream product

• 27068-89-9 3-hydroxy-2-p-tolyl-2,3-dihydro-5H-benzo[b][1,4]thiazepin-4-one 
• 107-99-3 2-(dimethylamino)ethyl chloride 
• 145475-96-3 5-(2-Dimethylamino-ethyl)-2-p-tolyl-5H-benzo[b][1,4]thiazepine-3,4-dione 
• 136620-24-1 2-(p-tolylmethylsulfanyl)aniline 
• 145475-95-2 N-(2-Dimethylamino-ethyl)-N-[2-(4-methyl-benzylsulfanyl)-phenyl]-oxalamic acid ethyl ester 
• 145475-94-1 N-[2-(4-Methyl-benzylsulfanyl)-phenyl]-oxalamic acid ethyl ester 
• 145475-93-0 (4-methylbenzyl)(2-nitrophenyl)sulfane 
• 104-82-5 4-Methylbenzyl chloride 
• 4875-10-9 o-nitrothiophenol 

Relevant academic research and scientific papers

A new synthetic route to 1,5-benzothiazepines. Synthesis of derivatives of diltiazem

Several derivatives of diltiazem (9a-c) have been synthesized from the oxamate (6) through the carbon-carbon ring closure of the sulfur-stabilized benzylic anion and the ester carbonyl group, followed by stereoselective reduction of the C3-carb