23441-10-3Relevant articles and documents
Johnson et al.
, p. 573 (1969)
Discrimination of Spermidine Amino Functions by a New Protecting Group Strategy; Application to the Synthesis of Guanidinylated Polyamines, Including Hirudonine
Mitchinson, Andrew,Golding, Bernard T.,Griffin, Roger J.,O'Sullivan, Mary C.
, p. 2613 - 2614 (2007/10/02)
Agmatine and hirudonine, guanidine derivatives of putrescine and spermidine, respectively, are synthesised by the application of a new protecting group strategy for polyamines, which uses N-nitroguanidinyl as a precursor of guanidine functions and selectively blocks spermidine at N-1 and N-8 with trifluoroacetyl and at N-4 by 4-azidobenzyloxycarbonyl.