234433-20-6

Basic information

• Product Name: Butanoic acid, 4-(dimethylamino)-, [4-chloro-2-[[2-oxo-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-3(2H)-yl ]methyl]phenoxy]methyl ester
• CAS NO: 234433-20-6
• Molecular Formula: C23H23ClF3N3O5
• Molecular Weight: 513.901
• Mol File: 234433-20-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 4-(dimethylamino)-, [4-chloro-2-[[2-oxo-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-3(2H)-yl ]methyl]phenoxy]methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 4-(dimethylamino)-, [4-chloro-2-[[2-oxo-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-3(2H)-yl ]methyl]phenoxy]methyl ester(234433-20-6)
• EPA Substance Registry System: Butanoic acid, 4-(dimethylamino)-, [4-chloro-2-[[2-oxo-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-3(2H)-yl ]methyl]phenoxy]methyl ester(234433-20-6)

Safety Data

• Hazardous Substances Data: 234433-20-6(Hazardous Substances Data)

Upstream product

• 69954-66-1 4-(dimethylamino)butyric acid hydrochloride 
• 233676-45-4 3-[(5-Chloro-2-[(chloromethyl)oxy]phenyl)methyl]-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2(3 H)-one 
• 202821-81-6 3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)-phenyl]-1,3,4-oxadiazol-2(3H)-one 
• 233676-37-4 3-[(5-chloro-2-[(methylthiomethyl)oxy]-phenyl)methyl]-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2(3H)-one 

Relevant articles and documents

Synthesis of water-Soluble prodrugs of BMS-191011: A maxi-K channel opener targeted for post-stroke neuroprotection

A variety of water-soluble prodrugs of BMS-191011 was synthesized and evaluated for solution state stability and rate of conversion to BMS-191011 in rat and human plasma. The deoxycarnitine ester prodrug (11c) was selected for clinical evaluation based on