234446-86-7Relevant academic research and scientific papers
Estrogen receptor subtype-selective ligands: Asymmetric synthesis and biological evaluation of cis- and trans-5,11-dialkyl-5,6,11,12- tetrahydrochrysenes
Meyers, Marvin J.,Jun, Sun,Carlson, Kathryn E.,Katzenellenbogen, Benita S.,Katzenellenbogen, John A.
, p. 2456 - 2468 (1999)
We have recently reported that racemic 5,11-cis-diethyl-5,6,11,12- tetrahydrochrysene-2,8-diol (THC, rac-2b) acts as an agonist on estrogen receptor alpha (ERα) and as a complete antagonist on estrogen receptor beta (ERβ) (Sun et al. Endocrinology 1999, 1
