23450-59-1

Basic information

• Product Name: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[[4-(dimethylamino)phenyl]methyl]-
• CAS NO: 23450-59-1
• Molecular Formula: C13H15N3O3
• Molecular Weight: 261.28
• Mol File: 23450-59-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[[4-(dimethylamino)phenyl]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[[4-(dimethylamino)phenyl]methyl]-(23450-59-1)
• EPA Substance Registry System: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[[4-(dimethylamino)phenyl]methyl]-(23450-59-1)

Safety Data

• Hazardous Substances Data: 23450-59-1(Hazardous Substances Data)

Upstream product

• 1753-47-5 5-(4-dimethylaminobenzylidene)barbituric acid 

Relevant articles and documents

Mono C-alkylation and mono C-benzylation of barbituric acids through zinc/acid reduction of acyl, benzylidene, and alkylidene barbiturate intermediates

Through systematic exploration of reaction conditions, very efficient preparative procedures for obtaining large quantities of substituted 5-alkyl and 5-benzylbarbituric acids were developed. The procedure involves a two step preparation in which the second step is zinc dust/acid reduction. For preparation of 5-alkylbarbiturates, the first step is the preparation of either 5-acyl or 5-alkylidenebarbiturate. If 5-benzylbarbiturate is the target product, then the first step includes the preparation of 5-benzylidene. Regardless of the nature of the first step, all reactions presented synthetic yields around 90% and isolation and purification involves only crystallization.