23456-82-8

Basic information

• Product Name: 4-ethoxy-1H-indole
• Synonyms: 4-ethoxy-1H-indole
• CAS NO: 23456-82-8
• Molecular Formula: C10H11NO
• Molecular Weight: 161.20044
• Mol File: 23456-82-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 71℃
• Boiling Point: 309.008°C at 760 mmHg
• Flash Point: 113.308°C
• Appearance: /
• Density: 1.132g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.617
• Storage Temp.: 2-8°C
• PKA: 17.28±0.30(Predicted)
• CAS DataBase Reference: 4-ethoxy-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ethoxy-1H-indole(23456-82-8)
• EPA Substance Registry System: 4-ethoxy-1H-indole(23456-82-8)

Safety Data

• Hazardous Substances Data: 23456-82-8(Hazardous Substances Data)

Usage

General Description

4-ethoxy-1H-indole, also known as 4-ethoxyindole, is a chemical compound with the molecular formula C10H11NO. It is a derivative of the heterocyclic compound indole, and it contains an ethoxy group (-OCH2CH3) attached to the carbon 4 position of the indole ring. 4-ethoxy-1H-indole is commonly used in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It exhibits various biological activities, including anti-inflammatory, antifungal, and anticancer properties. 4-ethoxy-1H-indole is also used as a building block in organic synthesis and is of interest for its potential therapeutic applications.

InChI:InChI=1/C10H11NO/c1-2-12-10-5-3-4-9-8(10)6-7-11-9/h3-7,11H,2H2,1H3

Upstream product

• 2380-94-1 1H-indol-4-ol 
• 90734-98-8 4-ethoxyindole-3-carbaldehyde 
• 487-89-8 Indole-3-carboxaldehyde 
• 75-03-6 ethyl iodide 

Downstream Products

• 220657-59-0 4-ethoxy-1-methoxy-2-phenylindole 
• 90734-98-8 4-ethoxyindole-3-carbaldehyde 
• 220657-56-7 2,3-dihydro-4-ethoxyindole 

Relevant articles and documents

INDOLYL-PIPERIDINYL BENZYLAMINES AS BETA-TRYPTASE INHIBITORS

The present invention discloses and claims a series of substituted indolyl-piperidinyl benzylamines of formula (I), wherein R1, R2 and R3 are as described herein. More specifically, the compounds of this invention are inhibitors of β-tryptase and are, therefore, useful as pharmaceutical agents. Additionally, this invention also discloses methods of preparation of substituted indolyl-piperidinyl benzylamines. In one of the embodiments, there is provided the compounds of formula (I) wherein R3 is (II).

Antiviral indoleoxoacetyl piperazine derivatives

This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with indoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.