23459-19-0Relevant academic research and scientific papers
Selective reaction of benzyl alcohols with HI gas: Iodination, reduction, and indane ring formations
Matsumoto, Shoji,Naito, Masafumi,Oseki, Takehisa,Akazome, Motohiro,Otani, Yasuhiko
, p. 7254 - 7259 (2017/11/24)
Reactions of benzyl alcohols with HI in solvent-free conditions were examined. Three types of reactions (iodination, reduction, and ring formation) occurred depending on the degree of crowding around the benzyl position and the benzylic stabilization of substrates. Results also showed that the ring formation to give indanes proceeded efficiently when HI was used, and that compounds with electron-rich aromatic rings gave indane derivatives in good yields.
Metal-Free Domino One-Pot Decarboxylative Cyclization of Cinnamic Acid Esters: Synthesis of Functionalized Indanes
Gopi Krishna Reddy, Alavala,Satyanarayana, Gedu
, p. 12212 - 12222 (2016/12/23)
Trifluoroacetic acid promoted unprecedented domino reaction for the synthesis of diverse indanes starting from simple cinnamic acid esters is described. Their formation can be explained via acid triggered decarboxylation of cinnamic acid esters and subsequent inter/intramolecular cyclization. Overall process involves in the intramolecular cleavage of two σ-bonds (C-O and C-C) and inter/intramolecular construction of two/one C-C σ-bond(s). Significantly, this protocol was successful without the aid of any metal salts.
Acid-promoted SN1/E1 fragmentation/dimerization of 2-cumylmalonates
Reeves, Jonathan T.,Fandrick, Daniel R.,Tan, Zhulin,Song, Jinhua J.,Yee, Nathan K.,Senanayake, Chris H.
scheme or table, p. 3077 - 3080 (2009/10/04)
Several diethyl 2-cumylmalonates underwent fragmentation and dimerization in PPA at elevated temperatures to give 1,1,3-trimethyl-3-arylindanes in good yields. The same products were obtained from 2-cumylmalonic acid, ethyl 2-cumylcyanoacetate, and 2-cumy
