7572-79-4

Basic information

• Product Name: α,α,2-Trimethylbenzyl alcohol
• Synonyms: 2-(2-Methylphenyl)-2-propanol;2-(o-Tolyl)-2-propanol;2,α,α-Trimethylbenzyl alcohol;α,α,2-Trimethylbenzenemethanol;α,α,2-Trimethylbenzyl alcohol
• CAS NO: 7572-79-4
• Molecular Formula: C₁₀H₁₄O
• Molecular Weight: 150.2176
• Mol File: 7572-79-4.mol
• Article Data: 15

Chemical Properties

• Melting Point: 41 °C
• Boiling Point: 204.8°Cat760mmHg
• Flash Point: 102.7°C
• Appearance: /
• Density: 0.979g/cm³
• Vapor Pressure: 0.156mmHg at 25°C
• Refractive Index: 1.516
• PKA: 14.50±0.29(Predicted)
• CAS DataBase Reference: α,α,2-Trimethylbenzyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: α,α,2-Trimethylbenzyl alcohol(7572-79-4)
• EPA Substance Registry System: α,α,2-Trimethylbenzyl alcohol(7572-79-4)

Safety Data

• Hazardous Substances Data: 7572-79-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H14O/c1-8-6-4-5-7-9(8)10(2,3)11/h4-7,11H,1-3H3

Upstream product

• 932-31-0 ortho-tolylmagnesium bromide 
• 67-64-1 acetone 
• 42502-56-7 1,3-dihydro-1,1-dimethylisobenzofuran 
• 7399-49-7 1-methyl-2-(prop-1-en-2-yl)benzene 
• 75-16-1 methylmagnesium bromide 
• 577-16-2 2-Methylacetophenone 
• 676-58-4 methylmagnesium chloride 
• 74-88-4 methyl iodide 
• 118-90-1 ortho-methylbenzoic acid 
• 95-47-6 o-xylene 
• 55549-01-4 α,α-dimethyl-o-xylene α,α'-diol 
• 85681-40-9 2-chloro-2-(2'-methylphenyl)propane 
• 527-84-4 2-methylisopropylbenzene 
• 95-46-5 2-methylphenyl bromide 

Downstream Products

• 7399-49-7 1-methyl-2-(prop-1-en-2-yl)benzene 
• 527-84-4 2-methylisopropylbenzene 
• 85681-40-9 2-chloro-2-(2'-methylphenyl)propane 
• 94686-16-5 2,3-Dimethyl-2,3-bis-(2-methyl-phenyl)-butan 
• 13387-56-9 2-(o-tolyl)propyl-2-hydroperoxide 
• 643-58-3 2-methylbiphenyl 
• 134694-65-8 ethyl 2'-methylbiphenyl-4-carboxylate 
• 577-16-2 2-Methylacetophenone 
• 1208128-87-3 2-(2-ortho(2-bromoethyl)phenylpropyl)tetrahydropyran ether 
• 1208128-86-2 2-(2-ortho-(2-hydroxyethyl)phenylpropyl)tetrahydropyrane ether 
• 1208128-88-4 2-(2-ortho-(2-chloroethyl)phenylpropyl)tetrahydropyrane ether 
• 909796-72-1 2-(2-(3-(2-(7-chloro-2-quinolyl)vinyl)phenyl-3-oxopropyl)phenyl)propanol 
• 23459-19-0 1,3,3,4-tetramethyl-1-(2-tolyl)-2,3-dihydro-1H-indene 
• 55549-01-4 α,α-dimethyl-o-xylene α,α'-diol 

Relevant articles and documents

An Iron-Mesoionic Carbene Complex for Catalytic Intramolecular C-H Amination Utilizing Organic Azides

The synthesis of N-heterocycles is of paramount importance for the pharmaceutical industry. They are often synthesized through atom economic and environmentally unfriendly methods, generating significant waste. A less explored, but greener, alternative is

Selective reaction of benzyl alcohols with HI gas: Iodination, reduction, and indane ring formations

Reactions of benzyl alcohols with HI in solvent-free conditions were examined. Three types of reactions (iodination, reduction, and ring formation) occurred depending on the degree of crowding around the benzyl position and the benzylic stabilization of substrates. Results also showed that the ring formation to give indanes proceeded efficiently when HI was used, and that compounds with electron-rich aromatic rings gave indane derivatives in good yields.

Structure-reactivity relationship of trifluoromethanesulfenates: Discovery of an electrophilic trifluoromethylthiolating reagent

A family of electrophilic trifluoromethanesulfenates was prepared. Structure-reactivity relationship studies showed that the substituted groups on the aryl ring of the trifluoromethylthiolating reagent did not have an obvious influence on their reactivities. A simplified electrophilic trifluoromethylthiolating reagent 1c was then identified that can react with a wide range of nucleophiles such as Grignard reagents, arylboronic acids, alkynes, indoles, β-ketoesters, oxindoles, and sodium sulfinates under mild reaction conditions. A variety of functional groups were tolerated under these conditions.