234753-30-1

Basic information

• Product Name: (S,S)-8,11-14,17-tetraethyl-2,5-dimethyl-3,4-diphenyl-2,5,8,11,14,17-hexaazacyclooctadecane-1,6-dione
• Synonyms: (S,S)-8,11-14,17-tetraethyl-2,5-dimethyl-3,4-diphenyl-2,5,8,11,14,17-hexaazacyclooctadecane-1,6-dione
• CAS NO: 234753-30-1
• Molecular Weight: 578.842
• Mol File: 234753-30-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S,S)-8,11-14,17-tetraethyl-2,5-dimethyl-3,4-diphenyl-2,5,8,11,14,17-hexaazacyclooctadecane-1,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (S,S)-8,11-14,17-tetraethyl-2,5-dimethyl-3,4-diphenyl-2,5,8,11,14,17-hexaazacyclooctadecane-1,6-dione(234753-30-1)
• EPA Substance Registry System: (S,S)-8,11-14,17-tetraethyl-2,5-dimethyl-3,4-diphenyl-2,5,8,11,14,17-hexaazacyclooctadecane-1,6-dione(234753-30-1)

Safety Data

• Hazardous Substances Data: 234753-30-1(Hazardous Substances Data)

Upstream product

• 24426-33-3 N,N',N'',N'''-tetraethyltriethylenetetramine 
• 234753-26-5 (S,S)-1,2-bis(N-methyl-α-chloroacetamido)-1,2-diphenylethane 
• 22751-68-4 (S,S)-N,N'-dimethyl-1,2-diphenylethane-1,2-diamine 
• 234753-20-9 diethyl ((1S,2S)-1,2-diphenylethane-1,2-diyl)dicarbamate 
• 29841-69-8 (S,S)-1,2-diphenyl-1,2-diaminoethane 

Relevant articles and documents

Synthesis of chiral azamacrocycles using the bis(α-chloroacetamide)s derived from chiral 1,2-diphenylethylenediamine

Optically active diphenyl-substituted tetraaza-12-crown-4 diamide (10), tetraaza-15-crown-5 diamide (12), tetraaza-18-crown-6 diamide (11), and hexaaza-18-crown-6 diamide (9) ligands were prepared by treating the appropriate secondary diamines with the (R,R)- and (S,S)- forms of 1,2- bis(N-methyl-α-chloracetamido)-1,2diphenylethane (20). Macrocyclic diamides 9 and 10 were reduced to form the optically active diphenyl-substituted hexaaza-18-crown-6 (13) and tetraaza-12-crown-4 (14), respectively. Reduction of macrocyclic diamide ligands 11 and 12 gave a complex mixture of products from which the desired tetraaza-15-crown-5 and 18-crown-6 compounds could not be isolated. Dichloride 20 was prepared by treating the chiral forms of 1,2- diphenylethylenediamine with chloroacetic anhydride or chloroacetyl chloride. The crystal structures for the (R,R)-form of dichloride 20 and the (S,S)-forms of macrocycles 10 and 11 are reported.